Science confirms that catching a cold in the new crown has left us with "welfare"

Like the new coronavirus, some viruses that cause a cold (note that a cold is different from the flu) are also coronaviruses.
fact, many adults have been infected with these coronaviruses.
fortunately, infection with this type of coronavirus usually causes only mild respiratory symptoms.
, perhaps even luckier, because the immune system has a remarkable ability to "remember", the small cold also gave our immune cells an early understanding of the new corona virus.
in a research paper published today in the leading academic journal Science, scientists at the LA JOLLA Institute for Immunology reported their findings.
"We have now shown that in some people, T-cell memory pre-existing for cold coronaviruses can cross-react to new coronaviruses in precise molecular structures.
, one of the study's co-authors, said, "This may help explain why some people have mild symptoms after contracting the new crown, while others get very sick."
Alessandro Sette, who co-led the study, added: "Immune responses can be translated into varying degrees of protection.
stronger or better T-cell response may give you the opportunity to have a faster and stronger immune response.
study builds on a team of results published in the journal Cell by Professor Sette and co-ators.
They found that not only did patients infected with the new coronary virus produce a group of auxiliary T-cells specifically to identify the new corona virus, but about 50 percent of those who had not been infected with the new corona virus also had T-cells that knew the new corona virus.
in other words, their immune systems recognize fragments of viruses they have never seen before.
, reports from different regions, including the Netherlands, Germany, the UK and Singapore, suggest that the phenomenon is not unique to a particular region, but rather a global phenomenon.
, how do T-cells that "know the new crown" come about? Scientists speculate that it may have come from the cold coronavirus that people have been exposed to.
professor Sette, the coronaviruses that cause colds are "less dangerous cousins" of the new coronavirus.
To verify that exposure to these cold viruses leads to immune memory against the new coronary virus, in the new study, the scientists collected blood samples from healthy participants from 2015 to 2018 to study T-cells that specifically respond to the new corona virus.
researchers found that pre-existing memory T cells responded to a total of 142 ethnoptics on the new corona virus.
further analysis showed that a series of memory T cells produced by the participants who had not been exposed to the new coronavirus were cross-reactive to the new coronavirus and four cold-causing coronaviruses (HCov-OC43, HCov-229E, HCoV-NL63 and HCoV-HKU1).
discovery means that fighting a cold coronavirus can indeed teach T-cells to recognize fragments of the new coronavirus. The
researchers found in blood samples of participants who had not been infected with the new coronavirus that memory T cells had cross-reactions to 142 new coronavirus etosis (Image source: Reference: References: 2) Professor Sette said: "We used to know that there was a pre-existing immune response, and this study provides strong direct molecular evidence that memory T cells can 'see' very similar sequences between cold coronavirus and SARS-CoV-2.
" it is worth mentioning that the analysis shows that while some cross-reactive T cells target the S protein of the new coronavigic virus (the region where the new coronavigic virus identifies and binds to the host cell), some of the immune memory is targeted at other parts of the new coronavigic virus. the
researchers explained that the findings are significant because most of the candidate vaccines are primarily targeted at S proteins, and the findings raise the hypothesis that including more new crown targets may increase the potential for cross-reactive utilization and further enhance vaccine effectiveness.
1) Jose Mateus et al., (2020) Selective and cross-reactive SARS-CoV-2 T cell epitopes in unexposed humans. Science DOI: 10.1126/science.abd3871 Retrieved Aug. 5, 2020, from.