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    Home > Active Ingredient News > Immunology News > Science: Is oral polio vaccine really effective against SARS-CoV-2 virus infection?

    Science: Is oral polio vaccine really effective against SARS-CoV-2 virus infection?

    • Last Update: 2020-06-16
    • Source: Internet
    • Author: User
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    JUNE 14, 2020 /PRNewswire/ -- In a recent study published in the international journal Science, scientists from the U.SFDA and other agencies said researchers should test oral polio vaccine to see if it protects people from SARS-CoV-2 virus infection, which has been found to help the body fight off infections caused by other viruses, and has been shown to be safe over the yearsPhoto Source: NIAID Polio Vaccines, as the name suggests, can be used to help prevent poliovirus infection, which has been in use since the 1950s and consists of two types: inactivated vaccine (injection method) and detoxified vaccine (oral) which, when combined, almost eradicate polio, and found that the vaccine has a degree of immunity to infections such as bacteria and viruses, and the paper analyzed whether the vaccine can be effectively prevented by oral infectionsThe polio vaccine helps the body develop immunity against other infections because it activates the body's first immune line, the congenital immune response, in contrast to the ability to immune to the virus when an individual is infected with a specific virus, because the body can specifically produce antibodies against the virus infection, the study The researchers say the use of oral polio vaccine to activate the host body's first immune line to help effectively fight COVID-19 infection, and recent studies have shown that the SARS-CoV-2 virus inhibits the congenital immune response of patients with severe disease symptomsThe researchers recommend testing oral vaccines (not injections) because they do not activate the body's congenital immune system, which is currently approved in the United States, one of the countries most affected by the COVID-19 outbreak, and the researchers say there are small risks associated with using oral vaccinesIt may also produce circulating vaccine-derived poliovirus, which can occur after vaccination in a very small number of populations, most of which are children with inadequate or stunted immune systems, and if the vaccine is proven to be effective against SARS-CoV-2 infection, the benefits may far outweigh the disadvantages( Original origins: Konstantin Chumakov, Christine SBenn, Peter Aaby, et alCan existing live vaccines vaccines coVID-19?, Science (2020)DOI: 10.1126/science.abc4262
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