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Science mouse pluripotent stem cells successfully induced follicles

 Last Update: 2021-07-29
 Source: Internet
 Author: User

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induced pluripotent stem cells

hplc method development

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preface

Germ cells develop in the specific environment of the reproductive organs

Theoretical basis

During mouse development, the embryonic ovary originated from the primary mesoderm, followed by the middle mesoderm and the body cavity epithelium at the genital ridge

result

Based on the expression of the reporter gene, we determined a series of culture conditions to gradually reproduce the differentiation process of pluripotent stem cells into gonadal cells

in conclusion

Our research results show that mESCs can induce functional gonadal cells through a reliable differentiation process during culture

Original Search: Generation of ovarian follicles from mouse pluripotent stem cells

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