Science Sub-Journal: Antihypertensive drugs can help patients with non-cancerous brain tumors

Boston-A new study led by researchers at Massachusetts General Hospital (MGH) and Massachusetts Eye and Ear shows that the blood pressure drug losartan may benefit patients with neurofibromatosis type 2 (NF2) , This is a genetic disease associated with vestibular schwannoma

"Developing effective treatments to protect the hearing function of NF2 patients is an urgent unmet medical need

Losartan blocks a component of the renin-angiotensin system, which is not only involved in regulating blood pressure, but also in stimulating fibrosis and inflammation

At the clinic, I am going to translate these findings into the article's second author Konstantina Stankovic, MD, PhD, former chief otology division and Neurotology, Massachusetts Eye and Ear, now professor and head of the Department of Otolaryngology-Head and Neck Surgery Stanford University School of Medicine examines patient samples and data

These findings support the need for prospective clinical trials of losartan in patients with NF2 and vestibular schwannoma

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