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These cells are called preepicardial cells and form the epicardium that covers the outer surface of the heart
When in contact with cardiomyocytes (or cardiomyocytes), preepicardial cells further develop into epicardial cells, and play an important role in supporting the formation of the embryonic heart—for example, by promoting the maturation of nearby cardiomyocytes
Ott pointed out that scientists can trace the early stages of heart development and produce millions of cardiomyocytes from a single blood draw, but the formation of the heart structure is very complicated
The production of cells that play a key role in forming the structure of the heart is necessary for regenerative medicine strategies for heart disease
Journal Reference :
Jun Jie Tan, Jacques P.