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Scientists discover new target for solid tumor CAR-T therapy

 Last Update: 2022-05-09
 Source: Internet
 Author: User

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The key to CAR-T cell therapy is the genetic modification of a patient's T cells

Moffitt researchers are working to identify tumor markers that will make CAR-T an effective treatment for patients with solid tumors

The researchers then created CAR-T cells that targeted the OR2H1 protein

These combined data suggest that OR2H1 may be an effective target for CAR-T therapy in solid tumors

"Given that OR2H1 is expressed in a variety of histological subsets of solid tumors, including high-grade serous ovarian, lung, cholangiocarcinoma, prostate, and ovarian cancers of various other histologies, our work demonstrates that this treatment is effective in various

Alexandra L.

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