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    Home > Food News > Food Articles > Scientists discover that DNA methylation modifies the plant's biological clock cycle

    Scientists discover that DNA methylation modifies the plant's biological clock cycle

    • Last Update: 2021-04-22
    • Source: Internet
    • Author: User
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    In this study, Wang Lei’s team found that treatment with DNA methyltransferase inhibitors can significantly prolong the Arabidopsis circadian clock cycle, and that met1-3 mutants with reduced CG methylation and drm1 with non-CG methylation lost The four mutants of drm2 cmt2 cmt3 (ddc2c3) all showed the phenotype of prolonged circadian clock cycle.


    In order to explore the regulatory mechanism, the researchers used a joint analysis of transcriptome and Arabidopsis methylome data to identify 7 genes whose transcription levels were increased in met1-3 and ddc2c3 mutants, and the methylation level of the promoter region was significantly decreased.


    This research system analyzes the mechanism of SDC through the protein cascade degradation pathway SDC-ZTL-TOC1 mediated DNA methylation to finely regulate the circadian clock cycle, and also provides a theoretical reference for mammals or other eukaryotic DNA methylation to regulate the circadian clock cycle .


    Related paper information: org/10.


    org/10.
    1093/nar/gkab128" target="_blank">https://doi.
    org/10.
    1093/nar/gkab128
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