Scientists discover the body's natural alert to blood loss!

Scientists at the University of Virginia School of Medicine have identified a cluster of cells in the brain stem that control the body's response to severe blood loss

The discovery pinpointed a group of neurons that drive a response to maintain blood pressure during blood loss

"When blood is lost, the brain coordinates cardiovascular responses that support blood flow to key organs such as the heart and brain," said Dr.

under pressure

New findings from Dr.

The scientists determined this using advanced imaging techniques and optogenetics, which allow neurons to be controlled remotely using light

Decompensated bleeding is a precursor to hemorrhagic shock, during which the body begins to stop functioning

"Our study shows that reactivation of brain pathways that control blood pressure can effectively reverse cardiovascular collapse during decompensated bleeding

The scientists noted that several factors may have contributed to the decline in C1 neuron activity during episodes of decompensated bleeding

"These findings illuminate the importance of brain-body interactions during blood loss and provide a new perspective on the underlying causes of cardiovascular failure," Abbott said

Blood loss survey results released

The researchers published their findings in the scientific journal Cell Reports

This research was supported by the American Heart Association and the National Institutes of Health with grants 19POST34430205 and HL148004, HL28785 and HL074011, respectively

article title

Adrenergic C1 neurons monitor arterial blood pressure and determine the sympathetic response to hemorrhage