Scientists have built the world's first predictive model of the risk of interstity lung disease

According to Bao Chunde, professor of rheumatology at Renji Hospital, affiliated with Shanghai Jiaoba University School of Medicine
According to Bao Chunde, myopathic dermatitis (ADM) is a rare autoimmune disease with a very high death rate, which is good for people in East Asia. In addition to the serological marker of anti-melanoma differentiation-related gene (MDA5) antibodies, patients usually show characteristic rashes, relatively mild myopathy and rapid progression of interstitial pulmonary disease, when ADM patients are accompanied by interstitial pulmonary disease (ILD) often die within one year of onset of rapid progression of interstitial pulmonary disease and respiratory failure, a mortality rate of up to 50%-60% within one year.
Team has been working on the clinical and basic research of the disease for many years. The forward-looking observational cohort study, initiated by him, has been collecting ADM-ILD patients continuously and following them closely since 2012. After 7 years before and after the study, a total of 207 ADM-ILD patients were included, follow-up time of 78 months, is currently the largest internationally reported sample size ADM-ILD research queue.experts said that the publication of this results paper is conducive to further study of ADM patients with ilD pathogenesis, actively explore treatment methods, to improve the success rate of ADM patients treatment, reduce mortality.
study was supported by projects at the National Natural Science Foundation of China. (Source: Yuan Yu Huangxin, China Science Journal)
relevant paper information: