Scientists have developed a new compound that can inhibit HIV

Recently, in a new research report, researchers from Yale University have successfully tested the effect of a compound (http://www.chemdrug.com/sell/76/) on inhibiting HIV and protecting immune cells of the body, while the single dose of the drug (http://www.chemdrug.com/) can maintain the effect for several weeks Relevant research is published in the international journal Proceedings of the National Academy of Sciences Related trials (http://www.chemdrug.com/sell/24/) study in animal experiments, this compound is expected to become a candidate drug to enhance the current HIV treatment, while it does not increase toxic side effects Prior to this, researchers developed a new class of compounds based on computer and structural design methods, which can effectively target proteins that are critical to HIV replication Then the researchers optimized these compounds to enhance their potential, reduce their toxicity, and improve the characteristics of drug samples The purpose was to develop new potential preclinical candidate drugs After the joint study, the researchers successfully tested the candidate drugs in the mouse model with human erythrocytes and HIV infection In humanized mice, the compound can achieve the main goal of HIV therapy, inhibit the virus so that it can not be detected in the blood of patients, and protect immune cells from virus infection In addition, the compound can play a role in combination with currently approved HIV drugs The researchers found that the protective effect of a single dose of the compound might last for a month, while the compound could be transported with long-acting nanoparticles At present, the researchers found that the new compound can effectively improve the current HIV treatment, the researchers hope to be able to test its therapeutic potential as soon as possible and the effect of combination therapy on HIV infection.