Scientists simulate early human embryo development

Recently, the U.S. research team reported on a system that can successfully simulate critical processes behind the bed of human embryos, helping not only to enhance scientists' understanding of the early development of human embryos, but also to bypass bioethics issues related to human embryo research because the system uses human pluripotent stem cells in a strictly controlled environment. The paper was published in Nature.
research on early embryo development after bed has been limited, including the failure of cell culture methods to meet the best standards, and bioethic guidelines prohibiting the use of fertilized human embryos for more than 14 days.
human and mouse pluripotent stem cells (cell types that can differentiate into specializations) have been used to simulate embryonic development behind bed, but the success rate of such systems in reproducing critical developmental events has been limited.
University of Michigan at Ann Arbor have demonstrated a controlled environment for cultured human ergonomic stem cells that can improve the efficiency and repeatability of synthetic model systems. They developed a microflow device , consisting of three channels for placing materials that cells can embed , loading stem cells , and transporting factors that stimulate stem cell differentiation.
researchers were able to control the differentiation of stem cells into major cell linees in early human embryos, producing synthetic embryo-like sacs. These sacs lack the specific cell types that produce living embryos. They also identified specific cell types that drive key events in embryonic development
(Source: Tang Erdu, China
)