Scientists use chemical catalytic reductive amination to achieve efficient synthesis of unnatural amino acids

Recently, the team of Yin Qin, associate professor of School of Pharmacy, Shenzhen University of Technology, Chinese Academy of Sciences (tentative name), associate researcher of Institute of Biomedicine and Technology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, and Zhang Xumu, professor of Southern University of Science and Technology, cooperated on the basis of previous cooperative research (J 2018, 140, 2024.

Chiral unnatural α-amino acids play a very important role in biology, biochemistry, medicine and materials science.

Biocatalysis provides a variety of means for the synthesis of unnatural α-amino acids, usually without the manipulation of protecting groups and under mild conditions

Relevant research work has been funded by the National Natural Science Foundation of China, the Natural Science "Outstanding Youth" Fund of Guangdong Province, and the Start-up Fund of Shenzhen Science and Technology