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Researchers at the University of California, Los Angeles, successfully transferred the memory of one sea rabbit to another using RNA (ribonucleic acid), according to a study published Thursday in the online journal eNeuro of the American Society for Neuroscience.
researchers say the new study will help develop new therapies to restore human memory.
sea rabbit, also known as sea otter, is a kind of snail.
the central nervous system of the hare has about 20,000 neurons, and although far from comparable to the 100 billion neurons in humans, its cells and molecules operate very similar lying with human neurons and are considered an excellent model for studying the human brain and memory.
In the study, researchers enhanced their defensive shrinkrerere reflex, a contraction reaction used to protect themselves from potential harm, by inflicting a slight electric shock on the sea rabbit.
after being "trained" with an electric shock, the sea rabbit shrinks for a long time during the touch, lasting up to 50 seconds, compared with a normal sea rabbit's contraction reaction lasting only 1 second.
, the researchers then extracted RNA from the nervous system of the "trained" sea rabbit and the normal sea rabbit, respectively, and injected it into the body of the rabbit, who had not received any electric shock.
they found that sea rabbits injected with "trained" sea rabbit RNA showed a defensive contraction response of up to 40 seconds when they were touched, compared with those that were not electrocuted sea rabbit RNA.
this suggests that, through RNA injections, the "trained" sea rabbit's shock memory is transferred to the new receptor.
researchers say their research is important in developing new therapies to restore human memory. In the near future, scientists may be able to use RNA to improve the effects of Alzheimer's disease or post-traumatic stress disorder and restore dormant memory in these patients, said David Glanzman, senior author of the
study and a professor of neurobiology at the University of California, Los Angeles.
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