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    Home > Active Ingredient News > Immunology News > Semin Arthritis Rheu: Pseudo-tumor calcium composure of systemic sclerosis

    Semin Arthritis Rheu: Pseudo-tumor calcium composure of systemic sclerosis

    • Last Update: 2020-05-29
    • Source: Internet
    • Author: User
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    The purpose of this study is to clarify the definition, distribution, clinical association and outcome of large calcium composure in patients with systemic sclerosis (SSc)researchers conducted a systematic literature review (SLR) for SSc-related large calcification blocksFollowing the updating of terminology and definitions, all cases of "pseudo-tumor" calcium calcium stoidation found at The University Hospitals of Cochin and Padua were analysedSLR found 30 Cases of SSc, with large calcified blocks primarily defined as "tumor" or "pseudo-tumor"Of the 629 SSc cases included in the Cochin and Padua cohorts, 19 were living (3%) and 7 died with pseudo-tumor calciumOf these, the vast majority have severe vascular phenotymiesThe average age of the population as a whole (56 cases) was 59 to 11.4 years, and the median number of cases of calcium calcium was 7 (5-10)In 26 of the 56 patients (46.4%) were skin diffuse SScAnti-topological isomerase I and anti-filament antibodies were foundPseudo-tumor calcium composure is usually symmetrical and ranges in size from 2-15.5cmAlmost all patients (98 per cent) suffered multiple injuries: 52 per cent of hands/wrists, 29 per cent of shoulders and elbows, 20 per cent of hips and 25 per cent of spinal calcificationFistula/ulcers and infections were reported in 34 per cent and 23 per cent, respectivelyNeuropsychiatric pressure was found in 40% of patients with spinal calcification and 1 case of limb calcificationThere is no clear evidence of clinical and radiology improvement spree for any treatmentSome improvements were observed in 7 patients undergoing surgeryabout 3% of SSc patients will have pseudo-tumor calcium, usually symmetrical, and appear in multiple areas, without differences in skin subtypes, but often in patients with severe vascular phenotype Medication is ineffective, but surgery can be considered
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