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| Sequences within the genome play a key role in the adaptive evolution of shrimp |
From simple to complex
SSR expansion and adaptive evolution of shrimp genome
New mechanism for shrimp SSR expansion
SSR is involved in the expression regulation of genes related to shrimp salinity adaptation
Recently, the research paper "Simple Repeated Sequences Promoting Plasticity and Adaptive Evolution of the Shrimp Genome" led by the research group of Li Fuhua from the Institute of Oceanology of the Chinese Academy of Sciences was published online in "Communications-Biology".
This study aimed at the explosive expansion of simple repetitive sequences (SSR) in the shrimp genome, and proposed a new mechanism for the rapid expansion of SSR in the genome for the first time, revealing the key role of SSR in the plasticity and adaptive evolution of the shrimp genome.
Chinese Academy of Sciences
"Junk DNA" plays a key role in the adaptive evolution of shrimp
"Junk DNA" plays a key role in the adaptive evolution of shrimpIt is understood that SSRs are formed by repeating 1~6 bases in tandem.
In order to explore the distribution characteristics and functions of SSR, researchers from Li Fuhua's research group completed the whole genome sequencing and assembly of another species of shrimp, Penaeus chinensis, and constructed the chromosomes of Litopenaeus vannamei and Penaeus chinensis based on Hi-C sequencing.
Through comparative genomics analysis, researchers inferred that the explosive expansion of SSR occurred in the ancestral genome of shrimp, and the specific expansion of SSR also appeared after the differentiation of different shrimps.
Discovered for the first time a new mechanism for explosive expansion of SSR
Discovered for the first time a new mechanism for explosive expansion of SSRAccording to reports, this study found for the first time a new mechanism for the explosive expansion of SSR, which is different from the traditionally believed replication sliding mutation model.
Although Penaeus chinensis and Penaeus vannamei are closely related, there are significant differences in their ability to adapt to salinity.
The results provide new clues for elucidating the function of SSR in organisms and the evolution of crustaceans' adaptation to the environment, and also provide an important theoretical basis and data support for shrimp genome breeding and molecular improvement.
Associate researcher Yuan Jianbo and researcher Zhang Xiaojun of the Institute of Oceanology, Chinese Academy of Sciences , and Professor Wang Min of Nankai University are the co-first authors of the article.
Chinese Academy of Sciences
Related paper information: https://doi.
https://doi.
