Several harmful mutations lead to the decline of potato self-incision

self-defying is a common phenomenon in heterodof pollinators: after continuous multigenerational self-intercourse, physiological function decline occurs, which is manifested in decreased growth and decreased yield.
January 14, local time, the journal Nature Genetics published online the results of the analysis of the genetic mechanism of potato self-decline jointly completed by the Potato Science Research Institute of Yunnan Normal University and the Agricultural Genome Research Institute of the Chinese Academy of Agricultural Sciences (hereinafter referred to as the Genomics Institute). This is the second major theoretical breakthrough since the implementation of the "Excellent Potato Program", which aims to replace the tetrogen with a double and replace the potato with hybrid seeds.Zhang Chunzhi, the first author of the
paper and a postdoctoral doctor at the Genomics Institute, told China Science that a total of 344,831 harmful mutations were identified throughout the genome by resequencing 151 copies of the double potato. These harmful mutations are rich in the near grain region, making it difficult to remove them all through traditional hybrid recombination.
further analysis found that only 11% of the same harmful mutations were found between any two copies of the secondary material, indicating that the harmful mutations in the potato were specific to the product. This may be due to the long-term asexual reproduction of potatoes, genetic exchange between the product line is rarely caused. As a result, these harmful mutations can be kept in a hybrid state by carefully designed hybrid combinations to obtain F1 hybrids with hybrid advantages.
to further identify the genetic effects of these harmful mutations, the researchers constructed three secondary potato self-separated populations and developed a family-free genotype method. Based on this method, the team identified 15 extremely isolated regions from three groups, suggesting that these regions contain harmful mutations with large effects. Combined with esogeal analysis, the research team identified 5 pure lethality points and 4 positions affecting long-term potential. This suggests that multiple genes are associated with self-indessocisity decline.
study found that one of the fatal mutation ar1 genes controls the development of the embryo, a rare mutation in the potato population. "The harmful mutations of these large effects are mainly located in areas with higher recombination rates, indicating that they can be effectively removed through genetic recombination." Huang Sanwen, author of the paper and a researcher at the Genomics Institute, said.
Huang stressed that the study provides a very full theoretical basis for solving the problem of potato self-confessed decline, and for the first time fully reveals the regularity of plant self-relationship decline. However, it will take time to eliminate these self-degeneration genes through hybrid selection. (Source: Li Chen, China Science Journal)