Shaanxi Normal University has made important progress in the field of green selective silicon hydrogen bond oxidation

Oxidation is one of the most important reactions in organic chemistry Selective oxidation can be used to synthesize organic chemical products, material molecules, drug intermediates and complex molecules The development of green selective catalytic oxidation can achieve efficient and selective synthesis of the chemical products needed, and the reaction does not produce or produce less waste, to achieve efficient and atomic economic chemical reaction Silanol is an important component of materials, important chemical raw materials, organic synthesis intermediates, drug molecular units and organic catalysts Up to now, organic chemists have developed rhodium, ruthenium, palladium, gold, silver, titanium, tungsten and other catalytic oxidation reactions, realizing the reaction of silicon hydrogen bond oxidation to silanol, but inevitably forming the product of silicon ether in the reaction selectivity Potassium permanganate is often used as oxidant in the oxidation reactions of carbon carbon double bond and carbon carbon double bond Potassium permanganate can also be used to oxidize silicon hydrogen bond to silanol, but the reaction needs a dose of potassium permanganate, which will produce equivalent manganese dioxide waste in the reaction, and the substrate has great limitations Because manganese is a cheap and less toxic metal In recent years, organic chemists have developed heme and non heme structured porphyrin like manganese catalysts, which have been used in the hydrogen bonded oxidation of hydrocarbons However, there is no report on the use of manganese containing catalysts in the hydrogen bonded oxidation of silicon to silanol Recently, the "green catalytic synthesis team" of Professor Xiao Jianliang from the school of chemistry and chemical engineering of Shaanxi Normal University and the research team of Li Chaoqun took the electron rich bipyridine manganese as the catalyst and H 2O 2 as the catalyst As an oxidant, the high-efficiency selective oxidation of silicon hydrogen bond was realized under mild conditions, which solved the challenge of inevitable by-products of silicon ether in the synthesis of silicon alcohol by silicon hydrogen bond oxidation This research result was published online as VIP article in Angel W chem Int ed (angel W chem Int ed 2019, 58, 6380-6384), and was selected as cover article Wang Kaikai, a postgraduate, is the first author of the paper, Professor Xiao Jianliang and researcher Li Chaoqun are the co correspondents of the paper, and Shaanxi Normal University is the first signatory (photo source: angelw Chem Int ed.) the work was supported by the Central University Fund (gk201603052), general program of Shaanxi Provincial Natural Science Fund (2017jm2002), startup fund of Shaanxi Normal University, Yangtze River scholars innovation team Fund (IRT R33) and "111" talent introduction program (b14041).