Shanghai Jiaotong University innovatively proposed early diagnosis criteria for subclinical heart damage in patients with primary biliary cholangitis

Recently, a well-known international journal in the field of digestion, "Clinical Gastroenterology and Hepatology" ("Clinical Gastroenterology and Hepatology"), published online the originality of the teamwork between Professor Ma Xiong of the Affiliated Renji Hospital Gastroenterology Department and Professor Bu Jun of Cardiology Department Research papers

Cirrhotic cardiomyopathy is one of the complications of patients with end-stage primary biliary cholangitis, with a high fatality rate, but it is not clear whether there is subclinical cardiac involvement in patients with early primary biliary cholangitis without cardiac symptoms

Compared with the control group, patients with primary biliary cholangitis showed hyperdynamic myocardial contraction, subclinical myocardial edema, elevated extracellular matrix volume fraction, and characteristic delayed myocardial gadolinium enhancement

This clinical study used CMR for the first time to explore whether there is cardiac involvement in primary biliary cholangitis in non-cirrhotic stage without cardiac symptoms, and reached an original conclusion

The corresponding authors of the paper are Professor Bu Jun, Professor Ma Xiong, and Professor Jiang Meng from the affiliated Renji Hospital.