Shanghai Ruijin Hospital reported: How high is the neutralizing titer of serum Omicron after the third dose of inactivated vaccine?

As the new coronavirus Omicron mutant strain spreads globally and has a strong immune escape ability, it is very important to study the neutralizing antibody level after the booster vaccination of the inactivated vaccine, especially the neutralizing activity of Omicron

On December 18, 2021, Shanghai Ruijin Hospital reported on the medRxiv the neutralization titer of Omicron in serum after the third dose of Sinopharm Bio-Beijing Vaccine (BBIBP-CorV) inactivated vaccine

In this study, 292 medical staff were recruited and pVNT50 was used to evaluate serum neutralization activity

Studies have shown that 8-9 months after the second inoculation of BBIBP-CorV, the neutralizing activity of the serum against the original strain is completely lost

The researchers also tested the neutralization titers of the vaccinators' serum against the original strain of the new coronavirus and the Omicron mutant.

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