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    Home > Active Ingredient News > Infection > Shortage! Global rush to buy "vaccine bottles"! Small glass bottle into a new crown vaccine came out a big "bottleneck"

    Shortage! Global rush to buy "vaccine bottles"! Small glass bottle into a new crown vaccine came out a big "bottleneck"

    • Last Update: 2020-12-12
    • Source: Internet
    • Author: User
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    As new crown vaccines developed by multinational pharmaceutical companies enter the late-stage trial phase, countries are preparing for vaccination programs.
    the success of vaccine research and development is only the first step in a long journey, and a dose of the vaccine, from the laboratory to the final human inoculation, will also go through many challenges.
    the problem of research and development and mass production is solved, the problem of upstream and downstream industrial chain, which is closely related to it, cannot be ignored.
    : Don't underestimate the challenges involved, which require a combination of different supply chains, not just vaccines, but glass bottles, rubber plugs, paper labels, and if anything doesn't go wrong, the final vaccine product will be delayed.
    , glass bottles loaded with the vaccine are showing signs of scarcity at a time when the new crown vaccine is about to be mass-produced.
    vaccine is a chemical agent, once a chemical reaction with a glass bottle, it will be contaminated, resulting in safety hazards.
    the glass bottle used in the vaccine is not an ordinary glass bottle, but a mid-boron silicon glass bottle, its chemical properties are stable, water-resistant, acid-resistant.
    the United States, Europe and other countries have mandatory all injection preparations and biological agents using medium boron silicon glass packaging.
    china's medicinal glass products are currently from sodium calcium glass and low boron silicon glass to medium boron silicon glass transition.
    the end of July, China had approved seven new crown vaccines that had entered the clinical phase, all of which were made of medicinal glass for medium boron silicon.
    zhang Wenhong, director of the infection department at Huashan Hospital affiliated with Fudan University in Shanghai: The production of glass bottles for vaccines is more difficult than for vaccines.
    Cold chain transportation difficult new crown vaccine face temperature control test analysis agencies predict that if each person is vaccinated three times, the global penetration rate of the new crown vaccine reached 20%, the need for 5 billion vaccine bottles, the global penetration rate of 70%, the need for nearly 16 billion vaccine bottles.
    , almost all of the biopharmaceutical companies involved in the development of the new crown vaccine are lining up to snap up vaccine bottles.
    , Johnson and Johnson alone has purchased 250 million vaccine bottles, according to public data released by the company.
    vaccines are extremely sensitive to temperature, a WHO study estimates that up to 50 per cent of the world's vaccines are wasted each year, largely due to a lack of temperature control and complete cold chain logistics.
    two fast-growing companies, Pfizer and Modner, are currently developing mRNA, the Messenger RNA vaccine.
    Pfizer's vaccine must remain at minus 70 degrees Celsius because of the stringent temperature requirements, and a large amount of dry ice is now an alternative against the backdrop of insufficient ultra-cold and cryogenic freezer facilities.
    Pfizer has developed a special thermostat that uses dry ice to store vaccines for 10 days.
    in Massachusetts, Mark and his team are stepping up production of dry ice for vaccine manufacturers.
    U.S. gasoline demand fell during the new crown pneumonia outbreak, and some ethanol plants that produce carbon dioxide as a by-product were forced to close, leading to a shortage of carbon dioxide in the United States.
    tricky, dry ice is classified as a hazard in international cargo transport, and Lufthansa warns that dry ice reduces the ability of aircraft to transport vaccines, with limited amounts of dry ice on board, typically within 500 to 1,000 kilograms.
    air cargo capacity cannot be delayed in order for vaccines to be processed on a large scale, transported safely and distributed quickly.
    junjak, chief executive of the international air transport association, called it the "mission of the century" for the global air cargo industry, which estimates that 8,000 fully loaded Boeing 747 cargo planes will need to be operated immediately to meet capacity, based on a dose of new crown vaccine for each of the world's 7.5 billion people.
    addition, some countries are lagging behind in infrastructure, health standards, etc. , how to ensure the safe transport of vaccines and vaccination is also a difficult problem.
    WeChat Images- 20201130193058.png Toby Peters, Professor at the University of Birmingham, UK: You will find that in some regions and countries, 30 to 40 per cent of medical centres may not be able to provide electricity, and in some countries, less than 10 per cent of medical centres may have functioning refrigerators.
    the new crown vaccine has not yet been listed in many countries, even if the above-mentioned problems are solved, the vaccine will ultimately have to face every vaccinator.
    , according to the latest poll, people in 15 countries are on average 4 percentage points less willing to get a new crown than in August, compared with less than 50 percent of Americans who are willing to vaccinate.
    Sealing people's doubts about vaccinations to solve the "last kilometer" conundrum is that only when enough people are vaccinated can the new crown vaccine really help people fight the virus, which means that the last person vaccinated is more important than the first person to be vaccinated."
    how to eliminate resistance to the new crown vaccine could be the "last kilometer" on the journey to defeat the new crown virus.
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