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Should workers be careful even when they sigh tea?

 Last Update: 2022-04-20
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Hyperuricemia is an important risk factor for gout and accounts for a large proportion of inflammatory arthritis in men
.

Chronic hyperuricemia can lead to long-term deposition of monosodium urate crystals, damage joint structures, and affect quality of life

It accounts for a large proportion of inflammatory arthritis in men

Various factors affect serum uric acid (SUA) concentrations, including tea consumption (green, black, or other types) and other dietary factors
.

After water, tea is one of the most popular beverages worldwide, especially in Asia

The purpose of this study was to evaluate the association between hyperuricemia and the frequency of tea drinking in Guangdong working population after adjusting for sociodemographic factors, anthropometric biochemical indicators, and dietary factors
.

The risk of hyperuricemia was also assessed by gender

This cross-sectional study analyzed data from a dataset of healthy candidates maintained by the Southern Medical University in Guangzhou, China, which contains information about incumbents who visit Nanfang Hospital for health checks
.

We extracted data on individuals aged ≥18 who visited the hospital between 2015 and 2020

Figure 1

The characteristics of the 7644 study participants are shown in Table 1 and stratified according to the presence of hyperuricemia
.

A total of 3149 participants had hyperuricemia, which was significantly more common in men (77.

The characteristics of the 7644 study participants are shown in Table 1 and stratified according to the presence of hyperuricemia

Univariate logistic regression analysis revealed a significant association between hyperuricemia and tea intake (OR 1.

744, 95%CI 1.
481-2.
053, monthly to twice weekly vs never, P < 0.

Univariate logistic regression analysis revealed a significant association between hyperuricemia and tea intake (OR 1.
744, 95%CI 1.
481-2.
053, monthly to twice weekly vs never, P < 0.
001; OR 2.
444, 95% CI 2.
070–2.
886, ≥ 3 times per week vs never, P < 0.
001)
.
Other categorical features were also associated with hyperuricemia (Table 2)
.
Univariate logistic regression analysis revealed a significant association between hyperuricemia and tea intake (OR 1.
744, 95%CI 1.
481-2.
053, monthly to twice weekly vs never, P < 0.
001; OR 2.
444, 95% CI 2.
070–2.
886, ≥ 3 times per week vs never, P < 0.
001)
.
Other categorical features were also associated with hyperuricemia (Table 2)
.
Once a month to twice a week P P

After selecting potential risk factors in the univariate logistic model, multivariate logistic regression analysis was performed based on the frequency of tea drinking in the three models
.
The association between tea intake and increased risk of hyperuricemia remained significant in all models
.
In Model 3, the adjusted OR for hyperuricemia was 1.
30 (95% CI 1.
08-1.
56, P= 0.
006), and 1.
35 (95% CI 1.
11-1.
64, P=0.
003) for participants who drank tea ≥3 times per week
.
The results showed that tea drinking was an independent risk factor for hyperuricemia (Table 3)
.

Male participants had a higher prevalence of hyperuricemia than female participants
.
A gender-based subgroup analysis was therefore performed
.
This relationship between hyperuricemia and tea consumption in male participants remained significant in the three models
.
However, there was no significant relationship between hyperuricemia and tea intake in female subjects (Figures 2 and 3)
.
Male participants had a higher prevalence of hyperuricemia than female participants
.
A gender-based subgroup analysis was therefore performed
.
This relationship between hyperuricemia and tea consumption in male participants remained significant in the three models
.
However, there was no significant relationship between hyperuricemia and tea intake in female subjects (Figures 2 and 3)
.

This cross-sectional study analyzed the relationship between hyperuricemia and tea intake using data from the Southern Hospital Health Checkup Database and found that higher tea consumption was associated with a higher risk of hyperuricemia
.
This association persisted after adjusting for potential confounders, including age, sex, BMI, education level, smoking status, alcohol consumption, grilled or fried food intake, pickled or smoked food intake, salty food , overeating, eating out, midnight snacks, and biochemical markers (SCr, CHOL, TG, LDL-C, HDL-C, and FBG, determined by univariate regression analysis and published literature)
.
These adjustments did not change the results, suggesting that tea consumption was an independent risk factor for hyperuricemia
.
This cross-sectional study analyzed the relationship between hyperuricemia and tea intake using data from the Southern Hospital Health Checkup Database and found that higher tea consumption was associated with a higher risk of hyperuricemia
.
This association persisted after adjusting for potential confounders, including age, sex, BMI, education level, smoking status, alcohol consumption, grilled or fried food intake, pickled or smoked food intake, salty food , overeating, eating out, midnight snacks, and biochemical markers (SCr, CHOL, TG, LDL-C, HDL-C, and FBG, determined by univariate regression analysis and published literature)
.
These adjustments did not change the results, suggesting that tea consumption was an independent risk factor for hyperuricemia
.

This study showed that the frequency of tea drinking was positively associated with the risk of hyperuricemia in the Chinese working population in Guangdong Province
.
Subgroup analyses showed that this effect was more pronounced in men than in women
.
Well-designed cohort studies with precise measurements of tea consumption are needed to confirm this finding
.
Further studies are needed to elucidate the underlying mechanism
.
This study showed that the frequency of tea drinking was positively associated with the risk of hyperuricemia in the Chinese working population in Guangdong Province
.
Subgroup analyses showed that this effect was more pronounced in men than in women
.
Well-designed cohort studies with precise measurements of tea consumption are needed to confirm this finding
.
Further studies are needed to elucidate the underlying mechanism
.

Original source:

Li R, et al.
Tea Consumption is Associated with an Increased Risk of Hyperuricemia in an Occupational Population in Guangdong, China.
Int J Gen Med.
2022 Mar 10;15:2747-2757.
doi: 10.
2147/IJGM.
S355253.
PMID: 35300131; PMCID: PMC8922363.

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