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    Home > Active Ingredient News > Drugs Articles > Simple analysis of the common dust collection device of rotary tablet press

    Simple analysis of the common dust collection device of rotary tablet press

    • Last Update: 2013-05-02
    • Source: Internet
    • Author: User
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    In the whole pharmaceutical production process, tablet production occupies a considerable share, while tablet pressing equipment is the key equipment for tablet production In order to improve the quality of drugs, Zui can avoid all kinds of pollution and reduce errors in the process of drug production to a large extent It is necessary to carry out GMP certification for the whole process of drug production, and also put forward corresponding requirements for tablet pressing production equipment GMP (version 98) has made special provisions for pharmaceutical production equipment Article 31 of Chapter IV "the design, selection and installation of the equipment shall meet the production requirements, be easy to clean, disinfect or sterilize, be convenient for production operation, repair and maintenance, and be able to prevent errors and reduce pollution"; Article 32 "the surface of the equipment in direct contact with pharmaceuticals shall be smooth, flat, easy to clean or sterilize , corrosion resistance, no chemical change or absorption of drugs Lubricants, coolants, etc used in the equipment shall not cause pollution to drugs or containers " Because of its high output, stable quality and suitable for large-scale production, rotary tablet press has become the main equipment of tablet production, and is widely used in most pharmaceutical factories According to GMP requirements, rotary tablet press must have dust suction device The following focuses on the causes of dust produced by rotary tablet press, the necessity of increasing dust collection and the comparison of commonly used dust collection devices 1 Working principle of rotary tablet press the main working process of the rotary tablet press is filling, pressing and discharging The granular material falls into the feeder through the hopper, depending on the self weight of the material or is forced to fall into the middle die hole, the upper punch rod and the lower punch rod rotate along the rail guide, and the material is pressed into pieces through the upper and lower pressure wheels, and then the pressed pieces are pushed out of the middle die hole through the upper rail guide of the lower punch, and then flow into the sheet groove 2 Causes of dust produced by rotary tablet press the main causes of dust produced by rotary tablet press are as follows: (1) dust produced in the process of manual feeding (2) for the ordinary feeder, the height of the feeding hopper is not adjusted properly, resulting in the gap between the hopper and the grid feeder is too large, and dust will also be generated during feeding (3) for the forced feeder, the connection pipe between the feeding hopper and the forced feeder is not tightly sealed, and dust will also be produced during feeding (4) the dust produced by the phenomenon of powder leakage due to the excessive clearance between the bottom surface of the ordinary feeder or the powder scraper and the plane of the turntable (5) dust produced by overflow phenomenon due to mismatch between material flow rate and rotary table speed (6) due to wear caused by long-term use of the punching rod, the gap between the punching rod and the die hole in the turntable is too large, resulting in dust produced by the phenomenon of "powder suppression" in the process of tablet pressing    3 It is necessary for rotary tablet press to increase dust collection The dust produced by rotary tablet press is easy to cause "plug flush", damage the rail guide, generate dust in the electrical cabinet, cause electrical circuit break, pollute the tablet press room, which is not suitable for cleaning and disinfection of the tablet press room, increase the wear of the mold hole in the turntable, waste materials, etc., so it is necessary to increase the dust collection device, recover materials, and improve the benefits of materials The utilization rate is in line with GMP In the production process of rotary tablet press, due to the feeding device or the reasons of adding materials, the dust is easy to fall into the middle punching plate At the same time, the matching gap between the lower punching rod and the lower middle plate is too large, which will also make the dust fall into the lower punching plate Therefore, the special dust suction device must be used to remove the imported dust pump Castel red wine 4 Comparison of dust collection devices 4.1 at present, the rotary tablet press generally uses the external dust collector to collect dust, which is mainly divided into mechanical dust collector, wet dust collector, electrostatic dust collector and filter dust collector, but the mechanical dust collector is commonly used, whose main structure is to collect dust through a vortex pump    Working principle of vortex air pump: the impeller of the air pump is composed of dozens of blades, which is similar to the impeller of the gas turbine When the impeller of the vortex air pump rotates, the air in the middle of the impeller blades is affected by the centrifugal force and moves towards the edge of the impeller, and moves away from the edge of the impeller with a certain centrifugal force, and enters the annular cavity of the pump body Because the centrifugal force and the special shape of the cavity are the same When it acts on the air, the moving air returns to the impeller and circulates again in the same way from the starting point of the blade As the air is accelerated evenly, the circulation air produced by the rotation of impeller makes the air flow out in the spiral motion track The air filtered by the filter belt is discharged into the room, which will produce slight dust to the indoor environment If the vortex air pump runs for a long time, the vortex motor will heat up and the pump is easy to block At the same time, the powder storage barrel produced by most manufacturers is not well sealed, which makes the dust collection effect of the vacuum cleaner poor 4.2 the other is built-in vacuum, as shown in Figure 2 The fan is located in the frame of the tablet press, the power is transmitted through the main motor, and the suction port is connected with the powder suction nozzle The suction port at the top of the tablet press chamber first draws air through the cyclone separation device, and then filters through the filter element The discharged air flows into the tablet press chamber from the annular air duct inside the base, thus forming the internal dust removal system of the rotary tablet press The cyclone separator of the device has simple structure, small floor area, convenient operation and maintenance, small pressure loss and small power consumption It is suitable for high temperature, high pressure and corrosive gases Even if the operation time is too long, the temperature rise of the motor is very low, which will not reduce the dust collection effect Conclusion through the comparison of the above vacuum devices, I personally think that the rotary tablet press Zui is a good choice for built-in vacuum to achieve a good vacuum effect.
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