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    Home > Active Ingredient News > Study of Nervous System > Simpler nerve stimulation can restore the fine hand movements of paralyzed animals|《Science·Translational Medicine》

    Simpler nerve stimulation can restore the fine hand movements of paralyzed animals|《Science·Translational Medicine》

    • Last Update: 2021-11-15
    • Source: Internet
    • Author: User
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    Click on the blue text above and pay attention to our electrical stimulation system that can restore the fine hand movements and grip strength of paralyzed non-human primates.
    This can be achieved by implanting only two electrodes around the peripheral nerves
    .

    This method can make electrical stimulation a more feasible clinical treatment option for patients with hand paralysis, because the current stimulation therapy is largely limited by poor selectivity and the need for complex surgical implantation of multiple electrodes
    .

    Stimulating the hand and arm muscles with surface electrodes can help people who are paralyzed due to spinal cord injury or stroke to restore some grasping ability
    .

    Implanting electrodes into muscles, rather than on the skin, allows researchers to stimulate deeper muscles in the hands and arms, thereby making greater progress in preclinical and early trials
    .

    In order to function effectively, intramuscular electrodes must be implanted through invasive surgery and must be placed in multiple muscles, some of which are difficult to do on the operating table
    .

    These difficult steps prevent the widespread use of electrical stimulation in the clinic, which indicates the need for simpler and less invasive strategies
    .

    Marion Badi and colleagues found that they only need to implant two electrodes into nerve fiber bundles called nerve bundles to effectively stimulate the hand and arm muscles of five paralyzed non-human primates
    .

    Their electrode system is called Mk-TIME, which can selectively touch specific hand muscles and restore the animal's hook grip, squeeze and other hand movements
    .

    In preliminary experiments, a trained, paralyzed non-human primate learned to use the brain-controlled version of the system to smoothly reach out for objects
    .

    The implanted electrodes also remained stable within 2 months, and the animals showed no signs of discomfort or pain
    .

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