Six genetic differences between the north and south have been revealed for the first time: southerners have stronger immunity.

Southerners have stronger immunity, the height of offspring or can be genetically measured? On October 10, Huada officially released the largest Chinese genomics big data research results to date at the Shenzhen National Gene Bank.
this is led by Chinese scientists, lasted two years, more than 14 million Chinese of non-invasive prenatal genetic testing data for the first time to reveal the genetic characteristics of the Chinese group of scientific research results, but also led by The University of China," "millions of people genetic big data research" project debut.
Chinese the six major genetic differences between the north and south were revealed for the first time: the southerner people's immunity is stronger, dr. Xu Xun, director of the China University Institute of Life Sciences and the first author of the article, said that the research results have two important significance, first, this marks the life science industry from the detection and diagnosis of a single sample, officially entered the era of genetic big data; Xu Xun,
, believes that the research results also prove that the life science industry has officially entered the era of genetic big data from the detection and diagnosis of a single sample.
it is understood that in 2016 Huada officially launched the "Million Sushuman Gene Big Data Research" project, this research project is the result of its first phase.
southerners have become more immune to the southerners in this study, Huada's team successfully built a Chinese gene frequency database (CMDB), including 9.04 million polymorphic sites, of which about 200,000 polymorphic sites were first discovered, which is the largest officially published database of Chinese group gene frequency.
noting that the team identified six genes that were strongly naturally selected in the latitude direction of the region, which showed significant north-south differences in genetic frequency, demonstrating the choice of diet, climate, pathogens and other environmental factors in the evolution of Chinese groups.
for example, because ancient areas such as Xinjiang, Qinghai and Inner Mongolia may have more difficult to obtain vegetables in ancient areas, resulting in a largeproportion proportion of meat intake of people living in these areas, so the allele of the gene that promotes fat metabolism rate has a clear tendency to enrich in these areas.
the gene CR1, which is associated with the body's immune function, is a southern cluster.
ancient South China is known as the southern barbarian, the natural environment is harsh, pathogenic microorganisms, especially malaria, so the survival of the region has higher immunity requirements.
, the ABCC11 gene related to wet and dry earwax, body odor (such as fox odor), sweat gland secretion, etc., also showed significant differences in choice between north and south.
without the Chinese in parts of Guangxi, Guangdong and Hainan without this genetic mutation.
the vast majority of people living in temperate climate areas in the north have this genetic mutation, the mutation is shown as dry earwax, less body odor, sweat gland secretion less, which may be more conducive to the northern living environment.
in the South, there is no natural selection pressure in this area, so that wild genes have been passed down in the South for a long time.
first discovery of the "baby twins" gene through data analysis, the team found and verified 48 height and 13 significantly BMI-related gene sites, including these sites, common mutation sites explained the height genetic rate of 48 percent and the BMI genetic rate of 10 percent.
as the study goes further, it is possible for scientists and algorithmic engineers to use this information to build height prediction models suitable for Chinese and to infer an individual's height from genetic data.
, the team analyzed two phenotypes of pregnancy age and twin pregnancy, and found two genetic sites that were significantly related to the age of pregnancy, suggesting that mutations in both sites were closely related to fertility;
Huada's research team also revealed for the first time the incidence of viral infections among the population of 31 provincial administrative units nationwide and the prevalence of the virus in plasma.
study found that the virus group Chinese plasma and Europeans have a large difference, for example, the top two in the European population are skin rash-related herpes virus 7 and nasopharyngeal cancer-related herpes virus type 4, while the first in the population in china is hepatitis B virus, the incidence of infection is about 2.5% Source: Science Daily.