Sleep after eating, increase the risk of gastroesophageal reflux by 12%!

Gastroesophageal reflux disease (defined as severe heartburn with or without reflux at least once a week) (GERD) is a common disease in pregnant women, usually due to changes in gastrointestinal motility caused by hormone changes.

Sleep studies shortly after eating a short time to fall asleep after feeding study (MTBT) and GERD (MTBT) with GERD incidence of morbidity associated with increased, especially in pregnant women associated with increased, especially in pregnant women population group .

In this study, 400 pregnant women (age> 18 years) at different stages of pregnancy were randomly enrolled.

In the study population, a total of 154 participants were diagnosed with GERD, with a total incidence of 38.

diagnosis

The total incidence of heartburn, reflux, nausea with or without vomiting, and epigastric pain were 11.

In the multivariate analysis, the shorter MTBT was the strongest predictor of GERD ( OR 12.

Shorter MTBT is the strongest predictor of GERD ( shorter MTBT is the strongest predictor of GERD ( OR OR 12.

However, the study still has some limitations, including the inability to accurately record the diet of participants and the possibility of overestimating the ratio of risk factors due to the small number of patients with reflux-related insomnia.

This study is important because gastroesophageal reflux is a common problem during pregnancy.

The association between short-term MTBT and increased risk of GERD is almost universally recognized.

In this study, the dose response between MTBT and reflux was observed.

Previously, in January this year, according to a large prospective study involving 43,000 women in JAMA Internal Medicine published by Massachusetts General Hospital in Boston and Harvard Medical School , the results showed that improving diet and lifestyle can greatly reduce The risk of gastroesophageal reflux disease (GERD).

JAMA's improved diet and lifestyle can greatly reduce the risk of gastroesophageal reflux disease (GERD).

The study finally concluded that even with proton pump inhibitors (PPI) and/or histamine receptor antagonists (H2RA) for treatment, adherence to the five anti-GERD-related lifestyles still has a beneficial effect on improving the risk of GERD symptoms and can be prevented The incidence of GERD is nearly 40%.

Adhering to five anti-GERD-related lifestyles still has a beneficial effect on improving the risk of GERD symptoms, and can prevent nearly 40% of the incidence of GERD.

For each participant, score the five anti-GERD lifestyles according to different factors, from 0 to 5: no more than two cups of soda, tea or coffee per day; no smoking; normal weight (BMI≥18.

The multiple logistic regression model showed that compared with women who did not adhere to these five factors, women who reported all five anti-GERD lifestyle factors had a 50% lower risk of GERD symptoms (OR 0.
50).
Further analysis showed that the combined action of all five factors can reduce GERD symptom cases by 37%.

Women who reported all five anti-GERD lifestyle factors had a 50% lower risk of GERD symptoms (OR 0.
50).
Further analysis showed that the combined action of all five factors can reduce GERD symptom cases by 37%.
Women who reported all five anti-GERD lifestyle factors had a 50% lower risk of GERD symptoms (OR 0.
50).
Further analysis showed that the combined action of all five factors can reduce GERD symptom cases by 37%.

Failure to comply with each anti-reflux lifestyle factor is independently associated with an increased risk of GERD symptoms.
After adjusting for other variables, BMI was associated with the highest population attributable risk (19%), followed by physical exercise (8%), food intake (7%), beverage intake (4%) and non Smoking status (3%).

After adjusting for other variables, BMI was associated with the highest population attributable risk (19%), followed by physical exercise (8%), food intake (7%), beverage intake (4%) and non Smoking status (3%).
After adjusting for other variables, BMI was associated with the highest population attributable risk (19%), followed by physical exercise (8%), food intake (7%), beverage intake (4%) and non Smoking status (3%).

The researchers also further explored the relationship between GERD symptoms and antireflux drugs and lifestyle factors.
The presence of all five antireflux factors was associated with a 53% reduction in the risk of GERD symptoms or PPI and/or H2RA treatment initiation (HR 0.
47).
Among the 3625 women who reported regular use of PPI and/or H2RA and no GERD symptoms at baseline, adherence to all five lifestyle factors reduced the risk of GERD symptoms by 68% (HR 0.
32).

This is an important study that further supports the value of adjustment of certain lifestyle factors in reducing the risk of GERD.

For clinicians, whether pregnant or not, for all individuals, avoiding night eating and shortening the meal time are recommended appropriate behavioral interventions to recommend to patients with heartburn or reflux difficulties.
However, more research is needed in some areas.
The implementation of this research will help patients or ordinary people prevent and improve gastroesophageal reflux disease through behavior changes.

Original source:

Original source:

1.
Short Meal-to-Bed Time Is a Predominant Risk Factor of Gastroesophageal Reflux Disease in Pregnancy.
doi: 10.
1097/MCG.
0000000000001399

1.
Short Meal-to-Bed Time Is a Predominant Risk Factor of Gastroesophageal Reflux Disease in Pregnancy.
doi: 10.
1097/MCG.
0000000000001399

2.
Association of Diet and Lifestyle With the Risk of Gastroesophageal Reflux Disease Symptoms in US Women.
doi:10.
1001/jamainternmed.
2020.
7238

2.
Association of Diet and Lifestyle With the Risk of Gastroesophageal Reflux Disease Symptoms in US Women.
doi:10.
1001/jamainternmed.
2020.
7238 Leave a message here