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    Home > Active Ingredient News > Drugs Articles > Solve common problems of coating machine machinery and design, make fine equipment products

    Solve common problems of coating machine machinery and design, make fine equipment products

    • Last Update: 2018-09-20
    • Source: Internet
    • Author: User
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    [product information of chinapharma.com] in China, coating machine has developed for more than 30 years It is a kind of mechanical and electrical integration equipment, which is energy-saving, safe, clean, and in line with GMP requirements, for packaging sugar coating, organic film coating, water-soluble film coating and slow, controlled-release coating of Chinese and Western medicine, tablets, pills, pellets, pellets, pellets, etc The coating machine is to control the coated core in the roller of the coating machine through the programmable control system, so that it can continuously, repeatedly and continuously make complex track motion In the process of movement, the coating machine can be programmed and controlled by the control system According to the requirements of process sequence and parameters, the medium can be automatically sprayed on the surface of the chip core in the form of mist by the spray gun At the same time, the coating machine will also be provided with clean hot air filtered by 100000 levels by the hot air cabinet, which will penetrate the chip core gap layer The medium sprayed on the surface of the chip core is fully contacted with the hot air and dried gradually The exhaust gas is discharged from the bottom of the drum through the air duct by the exhaust fan after dedusting, so that the chip core forms a solid and smooth surface film Like many pharmaceutical equipment, coating machine also has some problems, such as mechanical problems, design problems and so on These problems are factors that affect coating quality, but also easy to be ignored in the process of operation If not solved in time, it will have an important impact on the quality of drugs For example, the spray gun bracket in mechanical aspect is inclined Most of the coating feeding ports are of circular door structure The circular door is divided into two left and right doors The spray gun bracket is installed on the right door The distance between the right door shaft and the bracket is relatively long, so a fixed screw position is basically installed in the middle However, in the long-term use of the coating machine, the door spindle of the door with the spray gun bracket will tilt down, causing the whole spray gun bracket to tilt down, especially in the coating process, causing the spray gun inside to be close to the tablet In other words, the distance between the spray gun and the surface of the tablet is different, which will directly affect the coating quality Another example is the design of exhaust system The design of the air exhaust system of the coating machine mainly has the following problems: some old coating machines still basically adopt the bag filter system, and the isolation part at the bottom of the bag is easy to be damaged; secondly, the bag filter cannot shake the bag for dust removal under the working condition; thirdly, the bag blockage is judged by manual, and there is no local display and remote display function of the differential pressure; Fourth, there is no bypass design for the exhaust unit during cleaning In addition, if the cleaning is not in place, it will also have an impact on the product, because the coating machine is the production equipment in direct contact with drugs, it must be thoroughly cleaned to make it meet the requirements of process sanitation Experts suggest that when cleaning the equipment, it is necessary to cut off the power supply, remove the dust and waste outside the equipment, connect the drain pipe and start cleaning the equipment It should be noted that the insulating water in the mixing barrel should be drained first, and the insulating barrel should be washed clean with drinking water, and the water should be drained out A certain amount of drinking water shall be added into the insulation barrel first, then the detergent shall be added, and then the inner wall shall be cleaned with a handle soft brush, the sewage shall be removed, and the drinking water shall be used for washing again Then add a certain amount of drinking water and cleaning agent, start stirring, discharge port to peristaltic pump and spray gun, start the peristaltic pump, open the spray gun, spray and clean the silicon rubber pipe, peristaltic pump, spray gun and spray pipe, then change to drinking water and spray repeatedly After cleaning, replace with purified water, then use 75% ethanol to clean and disinfect the whole spray device In the whole development process, the mechanical form of the coating machine has not changed much, and few enterprises can provide all-round equipment upgrading, replacement and transformation services The defects in design and manufacturing will not only increase the equipment cost of pharmaceutical manufacturers, but also have an important impact on the quality and safety of pharmaceutical products Therefore, no matter in equipment design, machinery manufacturing or equipment cleaning, coating machine enterprises should be refined and refined.
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