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Specificity of Gβγ subunits of the decoy complex before and after stimulation of α2a adrenergic receptors

 Last Update: 2021-12-24
 Source: Internet
 Author: User

Gβγ dimers are specific at synapses

Relatively little is known about the specificity of G protein α subunits to their homologous GPCRs and their downstream effectors, while Gβγ dimers regulate synapses by inhibiting the release of neurotransmitters containing vesicles from presynaptic neurons.

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_2a-Adrenergic receptor (α_2aAR), leading to the activation of heterotrimeric G protein, which is composed of Gα subunits and Gβγ dimers with different functions

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