State Drug Administration: Two drugs are converted from prescription drugs to over-the-counter drugs.

On July 22, the State Drug Administration issued the Announcement on the Conversion of Adapalin Gel and Dipyrite Cream to Over-the-Counter Drug (No. 85 of 2020), which converted two drugs from Arapalin gels and dipyrite creams from prescription drugs to over-the-counter drugs: Accessories: Over-the-Counter-prescription Drugs The specification model Arapalin gel instructions please read the instructions carefully and according to the instructions for use or under the guidance of the pharmacist to purchase and use the generic name of the drug: Adaparin gel product name: English name: Chinese Pinyin: "ingredients" s.s.s."s","sex""effect category" This product is a dermatology drug-type over-the-counter drug.
(indications) this product is suitable for local treatment of mild moderate common acne, mainly with acne, papules and pustules.
can be used to treat acne in the face, chest and back.
(spec) 0.1% (usage) to clean acne before bedtime, to be dry after the local application of a thin layer of the product, 1 time daily, take care to avoid contact with the eyes and lips.
clinical effect began 4 to 8 weeks after treatment, with a marked improvement after 3 months.
have found better tolerance in patients who have been treated with Adaparin for 6 months.
recommended assessing the patient's improvement after 3 months of treatment.
stop treatment or reduce the frequency of medication due to an irritating reaction, the frequency of medication can be restored or increased depending on the treatment tolerance.
increased amount of medicine does not enhance efficacy or speed up the start-up, but can cause redness, dandruff or other discomfort.
no studies on the effectiveness and tolerance of Adaparin gels in children younger than 12 years of age are not recommended for children under 12 years of age.
adverse reactions and post-market adverse reactions, skin and subcutaneous tissue common (1/100 to 1/10) skin dryness, burning and erythema and other skin irritation symptoms, not common (1/1000 to 1/100) contact dermatitis, discomfort, sunburn, itching, dandruff, acne aggravation.
there are also reports of adverse reactions such as skin pain, swelling, skin pigmentation, skin pigmentation, eye irritation, erythema, itching, swelling of the eyelids, facial edema, vascular edema, etc.
there have been reports of cases of burns at the site of drug use abroad, most of which are superficial burns, but there have also been reports of secondary burns reactions.
.Taboo 1. Prohibited for anyone who is allergic to this product and the ingredients contained therein.
2. Is disabled for vitamin A derivatives.
3. Acute or subacute dermatitis, eczema skin disease disease is disabled.
4. This product is prohibited by pregnant women and women planning to become pregnant.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
2. Accidental pregnancy should be immediately discontinued and a physician consulted.
3. Use during breastfeeding and do not apply to the breasts of nursing women in order to avoid accidental skin contact from infants.
4. Elderly patients should be used under the guidance of a physician.
5. This product and excipient components (e.g. parabens, propylene glycol, etc.) may cause allergic reactions (possibly late hair responses) and skin irritation, and a small area trial is recommended for the first time.
if an allergic reaction or irritation (such as burning, itching, redness, etc.) should be discontinued, and local drugs washed, if necessary, consult a physician.
if you have severe symptoms, seek medical attention immediately.
6. Please clean your hands after using this product.
if accidentally exposed to mucous membranes (eyes, mouth, nasal mucous membranes) or open wounds, they must be washed with warm water.
. Taking into account the slight irritation of this product, the simultaneous use of strong cleaning products and products that can cause dry or irritating skin (e.g. products with alcohol and exfoliating properties, etc.).
8. Exposure to sunlight and ultraviolet light can increase irritation.
therefore avoid sun exposure and UV exposure during treatment.
if sunburn is present, the treatment of this product must be postponed until the sunburn is fully recovered.
9. When sun exposure, the day before the sun exposure, the day before and the day after the use of this product.
10. Is disabled for allergic products, and allergy-free people use with caution.
11. The use is prohibited when the character of this character changes.
12. Please keep this product out of the reach of children.
13. If other medicines are being used, consult a physician or pharmacist before using this product.
(drug interactions) have not yet been found to have interacted with other drugs that may be used in the skin at the same time.
but should not use other valuric acid or other drugs with similar mechanisms at the same time.
Adaparin's transdermal absorption is so low that it is unlikely to interact with systemic drugs.
there is no evidence that the efficacy of oral medications such as birth control pills and antibiotics is affected by skin use.
product may have a mild local stimulating effect that can cause additional stimuli when used in conjunction with peeling agents, shrinkers or irritants.
, therefore, early morning use of other skin anti-acne drugs such as erythromycin (concentration of 4%), klinmycin lotion (1%) or benzoyl peroxide hydrogel (concentration of 10%), at night when using this product, to avoid mutual degradation of drugs or the production of abuild stimulus.
may interact with other drugs if used in conjunction with other drugs, consult a physician or pharmacist for details.
adapithin is a viraceparic acid compound that has been shown to have anti-inflammatory properties in both in vivo and in vitro inflammatory models.
adaparin's chemical structure is stable and not easily decomposed in air and light.
mechanism, Adaparin binds to the specific nucleus receptor, which, like vimeric acid, is different from viformacid, which is not binding to cytoplasm receptors that bind to proteins.
tests on skin medication using animal models made in mice have shown that Adaparin can treat acne and also play a role in the process of common acne and differentiation.
adappalin's mechanism is thought to reduce the formation of tiny acne by causing the hair follicle epithelial cells to differentiate normally.
in the standard anti-inflammatory analysis in the body and in vitro, Adaparin is superior to viformacid.
it inhibits the chemical cheming reaction of human polynuclear leukocytes, and inhibits the metabolism of polymorphic nuclear leukocytes by inhibiting the conversion of the lactation reaction of peanut tetraoleic acid into an inflammatory medium.
this suggests that Adapalin is used in acne cases to relieve inflammatory reactions mediated by cellular reactions.
human clinical trials have shown that Adaparin can relieve inflammatory responses to acne ( such as pustules and papules ).
the business name of the enterprise: production address: zip code: fax number: Web site: If you have any questions, contact the manufacturer with the manufacturer's specification, please read the instructions carefully and use them as described or purchase and use them under the guidance of the pharmacist. Drug Name: Diphatai cream English name: Chinese Pinyin: (ingredients) this product is a compound preparation, each 4 grams, containing methazole 0.2 grams, gram mebacillist 0.16 grams, acetate chlorpyrifos 8 mg.
auxiliary material is: "sex" (effect category) This product is a gynaecological drug type of over-the-counter drug.
(indications) are used for bacterial vaginosis, vulvacane odosis, trichomoniasis vaginitis.
(specifications) 4 grams (containing methazole 200 mg, gram mebacille 160 mg, chlorpyrifos 8 mg) (usage) vaginal administration, one at a time, 1 time per night, even 7 days for a course of treatment, after the first menopausal clean after discontinuation of the treatment repeated a course of treatment.
or as directed by a doctor.
(adverse reactions) occasional lysaves, vaginal burns, itching, or other mucosal irritation symptoms.
because this product can be absorbed from mucosa, long-term large-scale use can also produce the same adverse reactions as systemic medication: 1, can cause seizures and peripheral neuropathy, the latter is mainly characterized by numbness and sensory abnormalities in the limbs.
the long-term use of certain cases can produce persistent peripheral neuropathy.
2, other common adverse reactions are: (1) gastrointestinal reactions, such as nausea, lack of appetite, vomiting, diarrhea, abdominal discomfort, changes in taste, dry mouth, oral metal odor.
(2) reversible granules are reduced.
(3) allergic reactions: rash, urticaria, itching, etc.
(4) symptoms of the central nervous system, such as headache, dizziness, fainting, feeling abnormality, limb numbness, co-relief disorders and mental disorders.
(5) other serum amino transferase elevated, fever, cystitis, difficulty urinating, urine color blackened, etc. , are reversible, after stopping the drug to recover on their own.
(Taboo) 1. Banned for patients with allergies to this product or pyridine (miquine) drug.
2. Patients with active central nervous disorder and blood disease are disabled.
3. Pregnant women are disabled.
.Notes 1. This product is only for vaginal administration, avoid oral.
2. Please use the drug in accordance with the drug specification usage amount and the use instructions of the attached to the over-the-box packaging of the toser.
3. Avoid menstruation when using this product.
. Pay attention to personal hygiene during medication, prevent repeated infections, use condoms or avoid housing.
5. Women with no history of sexual life should be used under the guidance of a physician.
. Lactating women should stop breastfeeding when applying this product.
. If the drug site has a burning sensation, redness and swelling, etc. should stop the drug, and local drugs washed, if necessary, consult a physician.
8. The elderly use it with caution.
is not recommended for children.
. If allergic symptoms or adverse reactions to the central nervous system occur during use, the drug should be discontinued immediately.
10. Liver and renal function should be used with caution.
11. Blood venom should be used with caution.
12. Vaginal trichomoniasis treatment requires the treatment of their sexual partner at the same time.
13. No alcohol or alcoholic beverages are allowed during use of this product.
14. Avoid contact with the eyes.
15. Is disabled for allergic to this product, and allergy-free people use it with caution.
16. The use is prohibited when the character of the character changes.
17. Please keep this product out of the reach of children.
. If other medications are being used, consult a physician or pharmacist before using this product.
.1. Chlorine has been set to be contraindications with soap, potassium iodide, etc.
are also contnged with borax, bicarbonate, carbonate, oxide, lusphonate, phosphate and sulfate.
2. When this product is combined with tomycin, the latter can interfere with the removal of vaginal trichomoniase.
. Long-term large-scale use of the mucosa absorption, can also produce drug interactions similar to systemic drugs, such as inhibiting the metabolism of warfarin and other oral anticoagulants, interference with bithyl luna metabolism and serum amino transferase and lactic acid dehydrogenase assays, with liver particulate enzyme inducer or inhibitor, can speed up or slow the metabolism of this product in the liver.
4. If the drug may interact with other drugs in parallel, consult a physician or pharmacist for details.
the drug effects of the product contained in metaxazole as ananaerobic bacteria and anti-titer drugs; gram mybacillis is a broad-spectrum antifungal drug, the shallow, deep and a variety of fungi have antibacterial effects, its mechanism is to inhibit the synthesis of fungal cell membranes and affect its metabolic process;
three-drug combination has synergies, not only for simple fungal, bacterial or trichomoniasis infections, but also for mixed infections.
the name of the enterprise of the enterprise of the enterprise of the "storage", "packaging","""description revision","description revision","description","description","description:zip code:telephone number: fax number: web address: if you have any questions, you can contact the manufacturer if you have any questions."