Stocking up on the Lancet Study Selection on June 6, 2020

1Be alert to the risk of childhood Kawasaki disease during the outbreak of new crown pneumonia
DOI: https://doi.org/10.1016/S0140-6736(20) 31103-XBergamo, Italy is a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemicOver the past month, the region has seen a concentrated outbreak of Kawasaki disease, and researchers recently assessed the incidence and characteristics of Kawasaki-like disease during the SARS-CoV-2 epidemicdivided all patients in the region diagnosed with Kawasaki-like disease in the last five years into two groups, based on the symptoms of SARS-CoV-2 before or after the outbreak of the epidemic (group 1) or after (2 groups)Kawasaki disease and Kawasaki sample performance according to the American Heart Association indicator, Kawasaki disease shock syndrome (KDSS) is defined as circulatory dysfunction, according to the International Experimental Organization standard for pediatric rheumatism to define macrophage activation syndrome (MAS)Nasopharynge swab and mouth-swallow swab sampling for reverse transcriptase quantitative PCR assays, serological detection of SARS-CoV-2IgM and IgGgroup 1 consisted of 19 patients (7 boys, 12 girls; aged 3.0 years) and was diagnosed from 1 January 2015 to 17 February 2020The second group included 10 patients (7 boys, 3 girls; 7 years of age) diagnosed between 18 February and 20 April 2020, of which 8 were positive for G Or Ig or bothThere were significant differences between the two groups in morbidity (group 1 vs 2, 0.3 vs 10 per month), average age (3.0 vs 7.5 years), heart condition (2/19 vs 6/10), KDSS (0/19 vs 5/10), MAS (0/19 vs 5/10) and the need for complementary steroid therapy (3/19 cases of 8/10)2:of clinical characteristics of patients with new crown pneumonia in New YorkDOI: https://doi.org/10146/S0140-6736 (20) 31189-2
more than 40,000 covid-19 patients have been confirmed in New York City as of April 28, 2020, and researchers have recently examined epidemiological, clinical and pre-expected data on the covid-19 outbreak in the New York arearesearchers collected data on adult patients with new coronary pneumonia between March 2 and April 1, 2020, with a total of 1,150 confirmed patients, 257 of whom were critically ill, with an average age of 62 years, 67 percent of men, 82 percent with other chronic diseases, the most common being high blood pressure (63 percent) and diabetes (36 percent), and 46 percent of obese patientsAs of 28 April 2020, 101 (39 per cent) patients had died and 94 (37 per cent) had continued to be hospitalizedSeventy-nine percent of patients received invasive mechanical ventilation for an average of 18 days, 66 percent received pressure hormone therapy and 31 percent received kidney replacement therapyThe average time for deterioration after hospitalization was 3 daysAfter multifactory adjustment, seniority (increased risk of 1.31 for every 10 years of age), chronic cardiovascular disease (1.76), chronic respiratory disease (1.76), an increase in interleukin 6 (1.11), and a high level of D-dipolymer (1.10) were important risk factors for hospital deathof study on the burden and risk factors
of diarrhoea in children in low- and middle-income countriesDOI: https://doi.org/10.1016/S0140-6736 (20) 30114-8in low- and middle-income countries (LMICs), one in ten children under five die from diarrhoeaDiarrhoea morbidity and mortality vary widely between countries, and researchers recently examined the risk factors associated with countries with the highest burden of diarrhoearesearchers used a Bayesian model dataset of 466 studies of 94 LMICs, comprising 1507,2746 children under the age of 5, combined with the results of the 2017 Global Study of Disease, Injury and Risk Factors (GBD), to estimate diarrhoea prevalence, morbidity and mortality rates in countries from 2000 to 2017The study found that the regions with the largest declines in diarrhoeal mortality were in South, South-East and South America, with units of 54.0 per cent, 17.4 per cent and 59.5 per cent, respectively, with a decline of more than 10 per centAlthough children in most parts of Africa still face a higher risk of diarrhoeal deaths, the region with the highest death toll is not In Africa, with the highest mortality units being in PakistanThe internal disparities are most pronounced in Indonesia, where mortality rates are almost four times the national average in some areasReduced mortality rates are associated with improvements in water, hygiene and personal hygiene (WASH) or reductions in child growth failure (CGF) Similarly, wash is poor in most high-risk areas, high CGF or low oral rehydration treatment coverage Source: MedSci Original