Focus on digestive health
Some people solve the matter of "tuba" in three minutes, and some people are still fighting hard in half an hour .
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Relying on "miracles" alone to fight constipation problems is dangerous, clinically, there are many drugs for constipation problems, today we will take a look at one of the commonly used drugs - lactulose medication specifications
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A
chronic habitual constipation is used in this way
▍Overview of domestic usage in adults:
Chronic functional constipation, chronic habitual constipation, regulate the circadian rhythm of the colon[1-2].
▍Usage and dosage:
Constipation and clinical need to maintain soft stools: oral, adults starting dose 30 mL daily, maintenance dose 10-25 mL
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After a few days of treatment, the dose
can be reduced according to the patient's condition.
This product should be taken once at breakfast, according to the mechanism of action of lactulose, 1-2 days can achieve clinical results, if there is no obvious effect after 2 days, please consult a doctor [2].
▍Overview of FDA usage in adults:
Treatment of constipation, in patients with a history of chronic constipation, lactulose solution may increase the number of daily bowel movements and the number of defecation days [5-6].
▍ FDA Dosage:
The usual dose is 1-2 tablespoons (15-30 mL containing 10-20 g of lactulose) per day
.
If necessary, the dose can be increased to 60 mL/day
.
Normal bowel movements may take 24 to 48 hours [5-6].
children have special attention to dose adjustment
Children 7-14 years of age: 15 mL daily for the initial dose and 10-25 mL
daily for the maintenance dose.
Children 1-6 years of age: 5-10 mL daily for the initial dose and 5-10 mL
per day for the maintenance dose.
infants: 5 mL daily initially, 5 mL daily for maintenance [2].
Because lactulose solutions contain galactose (total galactose<1.
6 g/15 mL), patients requiring a low galactose diet are contraindicated
.
What other medicines can be used for constipation?
Where to see more common drugs in gastroenterology?
Open "Clinical Decision Assistants - Evidence-Based Medicine"
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, Ltd.
, 2012/10/01
[2] Drug information: lactulose oral solution, Hunan Kelun Pharmaceutical Co.
, Ltd.
, 2015/12/01 [3]Product Information:GENERLAC-lactulose solution,Morton Grove Pharmaceuticals,Inc.
1/2019.
[4]Product Information:ENULOSE-lactulose solution,Actavis Pharma,Inc.
3/2016[5]Product Information:CONSTULOSE-lactulose solution,Actavis Pharma,Inc.
1/2017 [6] Product Information: KRISTALOSE-lactulose powder, for solution, Cumberland Pharmaceuticals Inc.
9/2018
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