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Patients with ischemic stroke caused by large atherosclerosis (LAA) or small vessel occlusion (SVO) usually do not receive long-term monitoring of atrial fibrillation (AF), and relevant secondary prevention guidelines do not recommend this approach.
In this group of people, it is unclear whether the insertable electrocardiogram monitor (ICM) detects a higher incidence of atrial fibrillation than the standard of care (SOC).
The research was announced at the 2021 International Stroke Conference (ISC2021).
Author: Medical team doctors report NMT NMT ISC finishing compiler, please do not reprint without authorization.
Study introduction STROKE AF is a multicenter, prospective, randomized controlled trial that compared the incidence of AF detected by ICM and SOC in LAA-IS and SVO-IS patients.
Eligible subjects should have no diagnosis of AF, age ≥60 years old (or 50-59 years old with stroke risk factors), ICM implantation ≤10 days after stroke, and no long-term oral anticoagulant (OAC) related Contraindications.
The study mainly compared the incidence of AF at 12 months between the two groups of subjects and plans to conduct a second analysis after 3 years.
Main research results: 492 subjects were finally included (242 in the ICM group, 250 in the SOC group).
Compared with the SOC group, the ICM group had a higher AF detection rate at 12 months (12.
1% vs 1.
8%; HR: 7.
41; 95% CI: 2.
6-21.
3; p<0.
001).
In the ICM group, the detection rate of AF in the LAA-IS and SVO-IS groups was similar (11.
7% vs.
12.
6%; p=0.
74), and 55.
5% of subjects had AF symptoms longer than 1 hour.Compared with the SOC group, the proportion of AF patients who used OAC to prevent stroke recurrence was higher in the ICM group (7.
4% vs 1.
2%; p<0.
001), and fewer patients had stroke recurrence (15 vs 23, HR: 0.
67; 95% CI: 0.
35- 1.
28; p=0.
23).
Conclusion In the ICM group, about 1 in 8 patients with LAA-IS or SVO-IS has AF detected.
Two-thirds of the patients had at least one AF symptom duration> 1 hour.
The results of this study suggest that AF may be a risk factor for stroke recurrence.
Therefore, long-term cardiac monitoring should be considered for patients with ischemic stroke presumed to be caused by LAA or SVO.
Yimaitong compiled from: Stroke AF: Atrial Fibrillation in Non-Cardioembolic Stroke of Presumed Known Origin.
ISC2021.
Lock the medlive-neurology channel (medlive-neurology), and check the latest information of ISC 2021 simultaneously! Long press the QR code to follow ☟☟☟ or click "Read the original text" to see more ISC 2021 topic related content!
In this group of people, it is unclear whether the insertable electrocardiogram monitor (ICM) detects a higher incidence of atrial fibrillation than the standard of care (SOC).
The research was announced at the 2021 International Stroke Conference (ISC2021).
Author: Medical team doctors report NMT NMT ISC finishing compiler, please do not reprint without authorization.
Study introduction STROKE AF is a multicenter, prospective, randomized controlled trial that compared the incidence of AF detected by ICM and SOC in LAA-IS and SVO-IS patients.
Eligible subjects should have no diagnosis of AF, age ≥60 years old (or 50-59 years old with stroke risk factors), ICM implantation ≤10 days after stroke, and no long-term oral anticoagulant (OAC) related Contraindications.
The study mainly compared the incidence of AF at 12 months between the two groups of subjects and plans to conduct a second analysis after 3 years.
Main research results: 492 subjects were finally included (242 in the ICM group, 250 in the SOC group).
Compared with the SOC group, the ICM group had a higher AF detection rate at 12 months (12.
1% vs 1.
8%; HR: 7.
41; 95% CI: 2.
6-21.
3; p<0.
001).
In the ICM group, the detection rate of AF in the LAA-IS and SVO-IS groups was similar (11.
7% vs.
12.
6%; p=0.
74), and 55.
5% of subjects had AF symptoms longer than 1 hour.Compared with the SOC group, the proportion of AF patients who used OAC to prevent stroke recurrence was higher in the ICM group (7.
4% vs 1.
2%; p<0.
001), and fewer patients had stroke recurrence (15 vs 23, HR: 0.
67; 95% CI: 0.
35- 1.
28; p=0.
23).
Conclusion In the ICM group, about 1 in 8 patients with LAA-IS or SVO-IS has AF detected.
Two-thirds of the patients had at least one AF symptom duration> 1 hour.
The results of this study suggest that AF may be a risk factor for stroke recurrence.
Therefore, long-term cardiac monitoring should be considered for patients with ischemic stroke presumed to be caused by LAA or SVO.
Yimaitong compiled from: Stroke AF: Atrial Fibrillation in Non-Cardioembolic Stroke of Presumed Known Origin.
ISC2021.
Lock the medlive-neurology channel (medlive-neurology), and check the latest information of ISC 2021 simultaneously! Long press the QR code to follow ☟☟☟ or click "Read the original text" to see more ISC 2021 topic related content!
