Stroke: Atrial fibrillation, which can predict the progress of indicators of cerebral small blood vessels

There is increasing evidence that atrial fibrillation (AF) is related to cognitive dysfunction, even in the absence of clinical stroke
.
Potential mechanisms for this association include cerebral thrombosis embolism and hypoperfusion, which is cerebral small blood vessel -related disease (SVD)

The current evidence linking atrial fibrillation with brain SVD markers mainly comes from cross-sectional studies, with mixed results.
Some studies report the relationship between atrial fibrillation and white matter hyperplasia (WMH) and brain atrophy, while others do not

Brain structural magnetic resonance imaging was performed at baseline (2001-2004) and follow-up (2004-2007 and 2007-2010)
.
The magnetic resonance imaging markers of SVD include perivascular space, lacune and white matter hyperplasia volume (WMH), lateral ventricle and total brain tissue

At baseline, 18 people (5.
4%) were identified as epidemic atrial fibrillation, and during the 6-year follow-up, 17 people (5.
6%) had atrial fibrillation
.

After multivariate adjustment, atrial fibrillation was significantly correlated with the annual growth rate of white matter hyperplasia volume (β=0.
45 [95% CI, 0.
04-0.
86]) and lateral ventricle volume (0.
58 [0.
13-1.
02])
.

Atrial fibrillation is not significantly related to the annual change in the number of perivascular spaces (β coefficient=0.

The important significance of this study lies in the discovery: atrial fibrillation, not related to cerebral infarction, is related to the accelerated progression of white matter lesions and ventricular enlargement in the elderly
.

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