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China is one of the countries with the heaviest stroke burden in the world.
Stroke In 2018, the number of deaths caused by stroke in China was 1.
Among them, AIS caused by middle cerebral artery (MCA) occlusion is an important subtype of acute anterior circulation ischemic stroke.
Compared with M1, although the M2 occlusion affects a smaller brain area, it still has a higher fatality rate (27%) and disability rate (57%), especially when the occlusion occurs in the dominant hemisphere.
Vascular Therefore, M2 endovascular occlusion therapy is still controversial.
To this end, experts from the Cerebrovascular Center of Bern University Hospital in Switzerland compared the effects of different treatments for patients with mild stroke and M2 occlusion, and the results were published in the latest "Stroke" magazine.
The study included patients with M2 acute occlusion who were eligible for intravenous thrombolysis (IVT) who were admitted to the Bern Stroke Center from January 2005 to January 2020 and had a National Institutes of Health Stroke Scale Score (NIHSS) ≤ 5 points.
A total of 169 eligible patients (38.
In general, the groups were similar in terms of gender, age, vascular risk factors, cause of the event, or pre-event independence.
Compared with patients with IVT only, there was no difference in the primary outcome (mRS=0-2) in the EVT (OR=0.
The researchers also pointed out that the demand for randomized controlled trials in this stroke area has not yet been met.
In summary, the study shows that only IVT and EVT (±IVT), and only IVT and MT are similar in effectiveness in patients with MCA occlusion and mild neurological impairment.
The study shows that only IVT and EVT (±IVT), and only IVT and MT are similar in effectiveness in patients with MCA occlusion and mild neurological impairment.
references:
Treatment and Outcome in Stroke Patients With Acute M2 Occlusion and Minor Neurological Deficits.
Treatment and Outcome in Stroke Patients With Acute M2 Occlusion and Minor Neurological Deficits.
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