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In previous studies, women had a higher risk of ruptured intracranial aneurysms than men, but women were not an independent risk factor
.
This may be due to a higher prevalence of female patients or aneurysm-related rupture risk factors compared with males, or the underpowered previous studies
Recently, the heart blood vessels published on the prestigious journal Stroke the areas of disease research article, the researchers aimed to assess gender differences aneurysm rupture rate, taking into account other risk factors associated with the patient and aneurysm ruptured aneurysm
.
The researchers searched Embase and Pubmed for articles published before December 1, 2020
.
This meta-analysis included cohorts for which individual patient data were available
hypertension
We pooled individual patient data from nine cohorts with a total of 9940 patients (6555 women, 66%), 12193 unruptured intracranial aneurysms, and 24357 annual follow-up visits
.
Ruptures occurred in 163 women (rupture rate 1.
CONCLUSIONS: Female patients have a higher risk of aneurysm rupture than males, and this gender difference cannot be explained by differences in patient- and aneurysm-related risk factors for aneurysm rupture
.
Future research should focus on explaining factors that explain the higher risk of ruptured aneurysms in women
Female patients had a higher risk of aneurysm rupture than males, and this gender difference could not be explained by differences in patient- and aneurysm-related risk factors for aneurysm rupture
Original source:
Charlotte CM Zuurbier.
