Stroke: hypotension after stroke, or increase the risk of death

High blood pressure (BP) is secondary to stroke and heart blood vessels a death disease recognized risk factors

In addition, some stroke patients had normal or low blood pressure levels at the time of the event; in a previously reported clinical trial, nearly 10% of participants had systolic blood pressure (SBP) <120 mmHg

The definitions of normal blood pressure and stage I hypertension are constantly changing

According to the results of the SPRINT (systolic blood pressure intervention trial), the primary prevention guideline for cardiovascular disease now recommends that the treatment target is SBP <130 mmHg.

The results of post-mortem analysis of clinical trials and observational studies indicate that low SBP (<120mmHg) may be harmful to the outcome (including mortality) of ischemic stroke

In this way, Hugo J.

They used a retrospective cohort study design .

The patients were followed up for 12 years to understand the main results of all-cause and cardiovascular deaths

Among 29,690 eligible stroke veterans (mean ± SD age 67 ± 12 years, 98% male, 67% white), 2989 (10%) had an average pre-stroke SBP <120 mm Hg

During the 4.

SBP<120 and 130 to 139 mmHg (hazard ratio=1.

Patients with an average SBP <120 mmHg and at least one comorbidity (smoking, heart disease, cancer, or dementia) have the highest risk of death (hazard ratio = 1.

The significance of this study is that it found that compared with normal blood pressure, pre-stroke hypotension is associated with post-stroke mortality, especially in patients with at least one comorbidity