Stroke: The determining factor in the presence and size of intracranial aneurysms in the general population
Last Update: 2020-06-16
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The prevalence of uncracked intracranial aneurysms (UIA) in adults is about 3%The potentially changeable determinants of intracranial aneurysm rupture can have fatal consequences, underscoring the potentially changeable determinants of the presence and size of UIAsIn a recent study published in Stroke, the authoritative journal for cardiovascular disease, researchers looked at the relationship between the underlying determinants of the average adult and the availability and size of UIABetween 2005 and 2015, 5,841 participants from the Rotterdam study (with an average age of 64.4 years and 45.0% of men) were examined for magnetic resonance imaging (1.5T)The researchers evaluated the results of these scans to determine whether there were UIAsThe researchers determined the number and volume of UIA, using logistic and linear regression models to assess the correlation between the presence and quantity of UIA and the determinants of cardiovascular, lifestyle, and new inflammation and hormonesOf the 134 (2.3%) participants, a uiA (a total of 149 UIAs) can be detected with a median volume of 61.1 mm3 (quart spacing of 33.2-134.0)In the multivariate model, women (ratio of 1.92 (95% CI is 1.33-2.84), hypertension (ratio of 1.73 (95% CI is 1.13-2.68)) and current smoking (ratio of 3.75 (95% CI is 2.27-6.33) are related to the presence or absence of UIThe researchers found that alcohol consumption, physical activity or the quality of their diet were not associated with UIAFinally, the researchers found that white blood cell counts were associated with larger aneurysms volume (the difference in white blood cell volume was 33.6mm3 for every 109/L volume increase (95% CI was 3.92-63.5)In this population-based study, women, high blood pressure and smoking were associated with UIAWhite blood cell counts are associated with the volume of UIAPrevention strategies should focus on treating high blood pressure and promoting smoking cessation
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