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Stroke: The effect of SGLT2 inhibitors on stroke and atrial fibrillation in patients with diabetic nephropathy

 Last Update: 2021-04-22
 Source: Internet
 Author: User

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Patients with chronic kidney disease who have a reduced estimated glomerular filtration rate or increased proteinuria have an increased risk of ischemic and hemorrhagic stroke .

Stroke, medsci.

The researchers randomly assigned 4401 participants with type 2 diabetes and chronic kidney disease to the canalidrinet or placebo treatment group.

diabetes

142 participants experienced a stroke during the follow-up period (10.

There was no significant effect on AF/AFL (HR: 0.

There is evidence that the overall impact of SGLT2i on stroke varies with the baseline estimated glomerular filtration rate (P=0.

It can be seen that SGLT2i has no clear effect on overall stroke, but there is still some evidence that it has benefits in preventing hemorrhagic stroke and AF/AFL.

SGLT2i has no clear effect on overall stroke, but there is still some evidence that it has benefits in preventing hemorrhagic stroke and AF/AFL.

Original source:

Zien Zhou.

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