STTT Wei Wensheng's research team and collaborators report a new mechanism for the new coronavirus to activate the host's natural immune response

Nian 2021 11 Yue 3 days, Beijing University and the Chinese Academy of Medical Sciences Wei Wensheng research group / Beijing Union Medical College Wang Jianwei Task Force cooperation in Signal Transduction and Targeted Therapy magazine published an article entitled Sensing of cytoplasmic chromatin by cGAS activates innate immune response in SARS-CoV The research paper of -2 infection reported a new mechanism for the new coronavirus to activate the host's natural immune response

The 2019 new coronavirus disease ( COVID-19 ) caused by the new coronavirus infection has severely affected human health and social stability, but its pathogenic mechanism is still unclear

The new coronavirus is a type of RNA virus, which is usually recognized by the host RIG-I -like receptor ( RLR ) and activates the interferon response

Figure 1.

The classic paradigm of innate immune response is a specific response to pathogen invasion after the body recognizes and distinguishes "self" and "non-self" components

Associate researcher Zhou Zhuo of Wei Wensheng's research group is the co-first author and co-corresponding author of the paper.

Original link: https://

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