Studies have shown that intraepithelial lymphocytes protect the intestinal tract from infection by harmful bacteria

Recently, in a new research report, researchers from Rockefeller University clarified how intraepithelial lymphocytes can protect the intestine from harmful bacteria In this paper, the researchers used new imaging techniques to assess the remote location of intraepithelial lymphocytes in mice The researchers found that epithelial lymphocytes are mainly responsible for monitoring specific parts of the gut barrier, and that when researchers interfere with the gut barrier's ability to sense harmful bacteria or manipulate the function of epithelial lymphocytes, mice become very sensitive to Salmonella This study elucidates a clear link between the body's gut barrier and its designated immune cells The results show that intestinal cell barrier tissue can remind the epithelial lymphocytes how to effectively distinguish the harmful bacteria and beneficial bacteria in the intestinal tract, which can help immune cells to effectively produce certain immune response to bacterial infection, and also provide new ideas and hopes for later researchers to develop corresponding therapies.