Studies have shown that younger diabetics have a higher risk of end-stage kidney disease.

Diabetic nephropathy (DN) has long been the leading cause of end-stage kidney disease (ESKD), accounting for one third of all cases worldwide.
But there is still little research on the long-term risk of ESKD in people with type 2 diabetes, especially since it is not clear whether the pathophysiology of DN in young diabetics differs from diabetes in older patients, or whether the long course of the disease will give DN more time and possibly develop ESKD.
recently published an article in the journal Diabetes Care entitled "The Association Between Age of The Type 2 Diabetes and the Long-Term Risk of End-Stage Kidney: A National Registry Study" that assessed the effect of age on the incidence of ESKD after the onset of type 2 diabetes.
study included 1,113,201 people with type 2 diabetes with a middle age of 58.1.
7,592 treated ESKD cases and 192,005 ESKD-free deaths during follow-up to 7,839,075 people.
5,671 cases of ESKD death in cases where kidney replacement treatment RRT has not been experienced, and the vast majority of these cases are of earlier age of onset.
characteristics of the study population ESKD incidence due to the age of the onset of diabetes, diabetes duration is also different.
study found that the incidence of ESKD increased with the duration of diabetes.
study found that the incidence of ESKD was higher in men than in women, and that there was a greater gender difference between those with diabetes before the age of 40 and those who developed diabetes after the age of 40.
the first 10 to 15 years of diabetes, the incidence of ESKD was higher among older people.
However, in cases where diabetes lasts longer, the incidence of ESKD is higher in young people with diabetes, and the higher the risk of ESKD in any given age group, the greater the impact of diabetes duration is substantially greater than the effect of age.
if untreated ESKD is included, older people with the disease still have a higher risk of ESKD in the first 20 years of diabetes, after which there is no significant difference in incidence among different age groups.
the cumulative incidence of ESKD in diabetic patients of different ages in the first 10-15 years of diabetes, young diabetics provided some protection for ESKD for a certain duration of diabetes.
because diabetes lasts longer, the cumulative incidence of ESKD is highest among young diabetics.
that among younger diabetics, men are at higher risk of developing ESKD than women.
in the first 20 years of diabetes, the cumulative incidence of diabetes was higher in older patients, after which the cumulative incidence in the various categories of onset age became more similar.
study on the cumulative incidence of ESKD in patients with type 2 diabetes with different durations of type 2 diabetes observed that the incidence of ESKD increased with the duration and age of diabetes, leading to a complex association between the risk of ESKD and the age of onset of diabetes.
in the first 10-15 years of diabetes, older people with diabetes had a higher risk of ESKD, and the younger the onset, the longer the course of the disease, the higher the risk.
However, since diabetes duration is a major determining factor in ESKD risk, and younger people with type 2 diabetes are more likely to survive longer diabetes durations, younger seizures clearly give a higher long-term risk of ESKD.
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