Study finds some 'sugar kids' are expected to throw away 'pots'
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Last Update: 2020-12-20
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Source: Internet
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Author: User
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Recently, the Shanghai Diabetes Research Institute, Shanghai Jiaoda University affiliated with the Sixth People's Hospital Liu Limei team found that in Chinese species, there is a special category of "MODY2 juvenile diabetes", such people can not take sugar-lowering drugs do not play insulin. The results were recently published in the international academic journal Metabolism.
can be broadly divided into three categories by cause: type 1 diabetes, type 2 diabetes and gestational diabetes. Adolescent adult type 2 diabetes is a type 2 diabetes differentiation from the early onset of diabetes, the age of onset is usually less than 25 years old, accounting for about 5% of the total number of diabetes, this type of diabetes due to the age of onset and type 1 diabetes overlap, clinical diagnosis is similar to type 2 diabetes, so clinically difficult to identify the cause of treatment, is the difficulty of diagnosis and treatment.
, it was widely believed that adolescent adults with developing diabetes caused by the disease-causing gene MODY2 were more common in Europeans, but rare in China. However, through genome-wide sequencing, molecular structure function analysis and personalized drug targeting treatment for large-scale familial adolescent diabetics, Liu Limei's team found that MODY2 type is not uncommon in China, accounting for about 10% of the proportion of adult developing diabetes patients in adolescents, the total number of moDY2 patients is estimated to exceed hundreds of thousands.
As a certified senior genetic consultant, Liu Limei in the clinical diagnosis at the same time found that after genetic diagnosis confirmed as MODY2 juvenile diabetes patients, only need to adopt appropriate dietary control, do not take sugar-lowering drugs, do not need insulin, you can achieve the ideal blood sugar control effect, will not cause other complications, prognosis is also very good.
" for MODY2 patients, if insulin, play less does not work, play more counterproductive, easy to cause hypoglycemia, and long-term drug vicious cycle, not only affect liver and kidney function, but also gastrointestinal reactions, harmful to health. Liu Limei said.
experts say the study suggests that the prevalence and number of moDY2 cases in China may be greatly underestimated. For MODY2 juvenile diabetes should be urgently started early precision prevention and control, which not only can save patients and the country a lot of economic savings, but also help to promote this group of adolescent diabetic children out of long-term drug pain. (Source: Xinhua News Agency, Wang Linlin)
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