Study found the first RNA silencing suppressor located in the Golgi apparatus

The tomato yellow leaf curl virus genome encodes multiple conserved open reading frames
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Gemini virus is a type of plant single-stranded DNA virus transmitted by insect vectors, causing devastating damage to economic and food crops such as tomato, tobacco, cotton, corn, wheat, and cassava on a global scale
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This study is based on the accumulation of previous studies on geminiviruses, combined with bioinformatics analysis, found that there are generally small open reading frames (ORFs) with unknown functions in the genomes of geminiviruses from different genera
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In-depth research on tomato yellow leaf curl virus (TYLCV), which is a serious production hazard, found that small ORFs can be transcribed and expressed during viral infection, showing specific subcellular locations, such as localization in the endoplasmic reticulum, mitochondria, and Golgi Body and other organelles
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Some small ORFs also have a transmembrane structure and are related to disease
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These research results expand the understanding of geminiviruses, and will greatly advance the understanding of the molecular mechanisms of the interactions between geminiviruses and host plants and even insect mediators
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The Institute of Plant Protection, Chinese Academy of Agricultural Sciences is the first unit of the thesis, Gong Pan, a doctoral student at the Institute of Plant Protection of the Chinese Academy of Agricultural Sciences, and Tan Huang, a doctoral student at the Center for Excellence in Molecular Plant Science, Chinese Academy of Sciences, are the co-first authors of the paper.
Plant Protection, Chinese Academy of Agricultural Sciences Prof.
Xueping Zhou and Prof.
Fangfang Li from the Institute and Prof.
Rosa Lozano-Duran from the Center for Excellence in Molecular Plant Science of the Chinese Academy of Sciences are the co-corresponding authors of the paper
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Related paper information: https://doi.