Summary of the topic of the schizophrenia susceptible gene ZNF804A.

In recent years, the Genome Wide Association Study (GWAS) has reported dozens of susceptible genes to schizophrenia.
ZNF804A is the first gene in Europe to be found to be significantly associated with schizophrenia using the GFAS method.
since 2011, Li Ming, a researcher at the Kunming Institute of Zoology of the Chinese Academy of Sciences, has conducted a series of studies on the ZNF804A gene, the results of which have been published in the journal American Journal of Psychia, Schizophrenia Research, World Journal of Biological Psython, American Medical Medical Genetics Part B: Neuropsychiatric Genetics and PLOS ONE.
with the increasing understanding of the function of the ZNF804A gene and its mechanism in schizophrenia, the susceptible gene has received more and more scholars' attention in the field.
In order to systematically understand the molecular mechanism of ZNF804A affecting the development of schizophrenia, Li Ming and his team members (Dr. Chang Hong and Xiao Wei of Kunming Animal Institute) systematically collated and analyzed the molecular mechanism of ZNF804A's influence on neurobiological level from genetic level to neurobiological level in recent years.
, they also explored the effects of ZNF804A on the "intermediate esoteric" of schizophrenia in cognitive biology, and highlighted the genetic susceptivity of the gene to heterogeneity among eurasian populations.
review article was recently published in the journal Molecular Psychiatry.
the work was supported by the "100-person program" pioneered by the Chinese Academy of Sciences.
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