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On April 14, Suoyuan Biopharmaceuticals and Rumpus Therapeutics/Aytu Biopharma signed a global license agreement for the development of DB102 (enzastaurin) for the treatment of vascular Ehlers-Danglos syndrome (vEDS) and other rare genetic diseases.
According to the agreement, Aytu BioPharma will be responsible for the clinical development and commercialization of DB102 for this rare disease, and will pay Suoyuan Biotech a milestone and sales commission of US$100 million.
(Note: Aytu Biopharma has officially acquired Rumpus Therapeutics)
vEDS is a rare genetic disease and a severe subtype of Ehlers-Danlos syndrome.
DB102 was originally developed by Eli Lilly and Company for the first-line treatment of newly-treated high-risk diffuse large B-cell lymphoma (DLBCL) and glioblastoma (GBM).