Super hematopoietic stem cells found in human embryos! The proliferation capacity is 200-500 times stronger.

In a recent study published in the international journal Stem Cell Reports, scientists from the University of Edinburgh and others have discovered a super-potential hematopoietic stem cell in human embryos that is commonly known as hematopoietic stem cells (HSCs, hematopoietic stem cells) that are commonly used in the development of new treatments for blood cancers and other cancers of the immune system.
through blood stem cell transplantation, healthy blood stem cells can replace diseased cells, which can potentially make all blood and immune cells, to achieve the goal of treating patients.
hematopoietic stem cells or formed cells are usually collected from donated umbilical cords, exoded blood, or adult bone marrow, but the supply of these cells has been a problem.
to overcome these limitations, researchers began looking for ways to expand the levels of available cells, such as by expanding to levels of artificial blood stem cells and achieving special differentiation and expansion of erypotent stem cells.
study, researchers found special hematopoietic stem cells from early human embryos that, when they first formed, were more likely to expand than stem cells in cord blood.
, the researchers compared hematopoietic stem cells in developing human embryos with cord blood to produce more hematopoietic stem cells during proliferation.
found that when transplanted into the mouse body, hematopoietic stem cells in embryos produced 200-500 times more hematopoietic stem cells than hematopoietic stem cells in umbilical cord blood.
researchers say it's important to understand why these hematopoietic stem cells in embryos can proliferate so powerfully, and the findings hope to help scientists expand hematopoietic stem cells from adult bone marrow later in life, thereby expanding the current clinical blood supply.
original source: Andrejs Ivanovs, Stanislav Rybtsov, Richard A. Anderson, et al. Vast Self-Renewal Potential of Human AGM Region HSCs Dramatic Declines in the Umbilical Cord Blood, Stem Cell Reports (2020) doi:10.1016/j.stemcr.2020.08.008 Original title: Super hematopoietic stem cells found in human embryos! Its proliferation capacity is 200-500 times that of hematopoietic stem cells in cord blood! This article is sourced from Bio Valley, for more information please download Bio Valley APP (