Synthetic biotechnology leads the development focus and direction of the bio-industry.

Synthetic biotechnology is spawning the third generation of biotechnology revolution after traditional industrial fermentation technology and large-scale gene manipulation technology, which is driving advanced chemical manufacturing towards a more efficient, intelligent, accurate and controllable direction.
below to learn about the development focus and direction of the bio-industry sector with a small compilation.
1, the diversified biomass resources of raw materials constitute the raw material foundation of biological industry development, and ensuring the cost, stability and availability of raw materials is an important prerequisite for industrial development.
for example, the domestic corn destocking policy in the next 3 to 5 years will bring benefits to qualified fuel ethanol processing enterprises and downstream enterprises such as sugar and starch, and promote the development of corn deep processing industry, in addition, plant, microbial and aquatic resources and waste are essential to establish a sustainable and productive value chain.
the use of single carbon raw material biotransformation: single carbon feedstock is widely used, it is also suitable for biocatalysts and biotransformation processes, the main single carbon feedstock includes methane, methanol, formaldehyde, formaldehyde and CO2.
methanol is used in much the same way as methane, and many microbes that use methane can also use methanol.
microalgae and cyanobacteria can also be used to convert CO2 into a variety of products, the biggest challenge of photosynthesis bioutilization is the need to create large areas of exposure, which need to be further improved and optimized.
another alternative to CO2 utilization is the combination of H2 and tolic acid to convert CO2 into a useful chemical. similarly
, syngas anaerobic fermentation, consisting of CO2, H2 and CO, has also been shown to be an effective way to produce fuels and chemicals from single-carbon feedstocks, and there will be significant investment opportunities in the future in converting syngas into a range of potential fuels, biopolymers, precursors, specialty plastics, nylon precursors, solvents and pharmaceutical precursors.
2, technology gene sequencing and synthesis, gene editing and other methods and technology and technology progress, a strong impetus to industrial biotechnology to more accurate and intelligent direction of in-depth development, the next generation of bio-industry innovation will be the combination of artificial intelligence, biological engineering and the Internet.
new tools and platform technologies: New tools and platform technologies have attracted investors' attention in recent years, DNA synthesis has rapidly become an investment hot spot to achieve rapid development and optimization of strains, the production of industrial chemicals and other bio-based products as the goal of robot automation, machine learning, innovative software and high-throughput screening technology integration research, will be in the future will be a great opportunity for development.
for example, the use of large data processing technologies and analytical platforms to conduct in-depth analysis of microbial genomes and metabolic pathways, the optimal design of high-efficiency enzymes in accordance with human aspirations through computer-assisted technology, the conversion of microbial, plant or animal cells into biofactories capable of producing new fuels, chemicals and even bio-computers, and the use of platform technology to provide cell engineering and analysis programmes based on CRISPR-Cas9 gene editing technology.
Microbiome solution: Microbiome refers to all microorganisms and their genetic information in a particular environment or ecosystem, including their cell population and number, and all genetic material.
human microbiome research helps to understand the role of microorganisms in health and disease, plant and soil microbiome research is beneficial to increased crop health, microbial compounds and bio-control products can be widely used in corn, soybeans, fruits and vegetables, to help plants absorb nutrients against pests, diseases and herbicides.
With the research of microbiome in the academic and industrial circles, the development of microbiome characteristic gene mining, microbiome health level, compound microbial preparation development and other work will also usher in the investment boom.
3, product synthesis biology is like a "toolbox" that can provide a complete set of genetic components, can realize the design and construction of new biological parts, devices and systems, and then replace the petrochemical process with biomass raw materials and biological processes low production costs, low quantities, high value of chemicals, as a large number of end products (such as plastics, lubricants, waxes and cosmetics, etc.) the basic building blocks, bio-based chemicals and materials global production capacity is expanding, the prospects are promising.
at the same time, the innovation of synthetic biotechnology will also give birth to more disruptive technologies and non-natural products, such as cobprotein, artificial animal protein and other products, bringing unprecedented applications.
Fine Chemicals: Many start-ups in the bio-industry focus on biochemicals with small production sizes but high added value that are not directly competitive with petroleum-based products, which often have special functional characteristics that are not available in similar products on the market and are more like complements to existing products than replaced.
such as functional nutrition and health products, fine daily necessities and personal care products, and high-performance textile and decorative materials, which are located in high-end consumer groups.
modern industrial biotechnology has the advantages of high efficiency, high selectivity, mild conversion conditions and environmental friendliness, which can complete some reactions that are difficult to achieve by traditional chemical methods, and are widely used to prepare a variety of high value-added chemicals, bringing considerable economic benefits and return on investment.
pharmaceutical chemicals: Pharmaceutical chemicals are undoubtedly a relatively high value-added category of bio-based products, natural drugs effective components and chemical synthesis of raw materials can effectively solve the pharmaceutical chemicalplant extraction or chemical synthesis route serious pollution, low synthesis efficiency and other issues, is to innovate traditional pharmaceutical processes and chemical processes, significantly reduce energy and water consumption, reduce environmental pollutant emissions, promote energy conservation and emission reduction, to ensure the coordinated development of the economy and the environment.
natural drugs such as artemisinin, ginseng saponin, red sky, as well as lincomycin, l-dopa and other drugs have achieved some or all of the biosynthesis route replacement, the future of such products will be more varieties, productivity is expected to further improve.
high-efficiency enzymes: compound enzymes with higher technical content and added value are important directions for the development of new enzyme products, and the rapid expansion of the market for functional foods and textiles has contributed to the market development of new enzymes.
in the field of food and beverage, with the increasing market demand to promote digestion and improve the value of nutrients, the consumption of enzyme preparations will be significantly increased;
4. The process of strengthening the construction of ecological civilization puts forward new and strict requirements for the environmental protection of industrial development, and green biological processbased on enzyme engineering and bio-catalyzing can play an important role in improving product quality, saving energy and reducing energy efficiency, reducing production costs and environmental protection.
environmental protection fee reform tax after the implementation of the high pollution, high emissions of paper, textile, leather and other industries will bring greater cost pressure, the recent strict environmental protection policy more directly on some of the production industry backward, emissions of enterprises that do not meet the standards of closure, forcing traditional enterprises to take the green development route, thus using biodegradation or biocatalytic technology routes of the industry will also usher in the golden development period.
The future development prospects of China's bio-industry are expected on November 7, 2017, the Tianjin Institute of Industrial Biotechnology of the Chinese Academy of Sciences and the Chengdu Documentation and Information Center of the Chinese Academy of Sciences jointly released the "White Paper on China's Industrial Biotechnology and The 2nd China Bio-Industry Investment Report 2017" at the 9th China Industrial Biotechnology Development Summit And the 2nd China Bio-Industry Investment Conference.
report noted that the global bio-industry has absorbed a large number of government, public and private sector investments in recent years, with more than $1 billion invested annually in synthetic biotechnology research and development, bio-based materials and chemical sdevelopment, creating an industry-rich and innovative ecosystem. At the same time
, China has made remarkable research results in synthetic biotechnology, bio-based chemicals, bio-based materials, microbial environmental management, biosensors, green bioprocesses, microbiodiversity research, etc. in recent years.
china's bio-industrial investment will also usher in a golden period under the influence of multiple factors such as the promotion of national industrial policy, the traction of technological progress, the active deepening adjustment of the industry and the growth of people's livelihood demand.
under the influence of the multi-factors of the national industrial policy promotion, technological progress traction, industry deepening adjustment and the growth of people's livelihood demand, the future development prospects of China's bio-industry are promising.
expects that by 2022, China's broad biological industry output value is expected to reach 10 trillion yuan, bio-based materials and chemicals (excluding biopharmaceutical products) replacement rate gradually increased, sales revenue in the total materials and chemicals market sales share is expected to reach 10%.
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