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    Home > Medical News > Medical Research Articles > Synthetic tissue model with blood vessels

    Synthetic tissue model with blood vessels

    • Last Update: 2021-09-04
    • Source: Internet
    • Author: User
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    Scientists work in a special hydrogel whose properties can be changed in a controlled way


    In summarizing these key findings, Britta Trappmann emphasized, “Synthetic tissue materials must activate certain adhesion molecules on the vascular cell membrane, allowing cells to migrate in groups from the mother’s blood vessel to form a tubular structure


    Three-dimensional tissue frame made of hydrogel

    In this study, the researchers perfected the model system that Britta Trappmann developed with colleagues when he was a postdoctoral fellow at Boston and Harvard University in the United States


    Then, the scientists wanted to find out which properties of the hydrogel determine whether the migrating endothelial cells actually form new blood vessels


    Integrin migration

    The higher the peptide concentration, the more endothelial cells migrate through the hydrogel


    Although blood vessel cells then form tubular structures, they are smaller than in natural tissues


    Journal Reference :

    1. Jifeng Liu, Hongyan Long, Dagmar Zeuschner, Andreas FB Räder, William J.



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