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Crohn's disease (CD) is a chronic gastrointestinal inflammatory disease characterized by relapse and remission.
about half of CD patients have intestinal complications, such as stenosis or fistula.
, close monitoring of disease activity throughout the disease of CD is essential.
currently, endoscopy is considered the primary means of checking the degree of disease relief of CD.
, however, endoscopy is invasive, uncomfortable, time-consuming and expensive, and not suitable for routine use.
, precise and reliable non-invasive alternative markers are needed to assess the severity of CD endoscope disease activity.
recent evidence of abnormal whole blood cell count (CBC) in CD patients.
many studies have found that some conventional CBC blood indicators, such as red blood cell distribution width, plate plate count, average plate plate volume, and plateboard generation ratio (PCT), can be used as biomarkers to monitor disease activity in CD patients.
some indirect parameters, such as the ratio of neophils to lymphocytes and plateboard to lymphocytes, have also been used to determine the activity of the disease.
therefore, the purpose of this study is to build a simple model consisting of blood parameters from traditional hematological tests that reliably reflect the severity of CD endoscopic disease activity.
researchers conducted a retrospective analysis of confirmed CD patients who underscopyed clinically at four level 3 medical centers in China between 2016 and 2020.
endoscopic score of CD, CBC parameters, C-reactive protein (CRP) level, individual variable rate of red blood cell seidation, and... MedSci Original Source: MedSci Original Copyright Notice: All text, images and audio and video materials on this website that indicate "Source: Mets Medicine" or "Source: MedSci Original" are owned by Mets Medicine and are not authorized to be reproduced by any media, website or individual, and are authorized to be reproduced with the words "Source: Mets Medicine".
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