Tamiflu's alleged limited utility Roche may hide relevant information

Source: from April 10, 2014 to November 10, 2014, the analysis report of the international evidence-based medicine collaboration group revealed that Tamiflu, a flu drug developed in the UK with a cost of 473 million pounds, is no better than paracetamol in the prevention and treatment of influenza, while the former is a drug reserved by governments around the world to deal with influenza pandemic Tamiflu is the exclusive anti influenza drug produced by Roche The report claims that Tamiflu does not prevent the spread of influenza or reduce the risk of complications, but only slightly relieves influenza symptoms The efficacy of Tamiflu is similar to that of paracetamol, and its effect is questioned But Roche, the manufacturer, and some other experts believe the analysis is flawed Since 2006, Tamiflu has been the UK's reserve drug for dealing with influenza pandemics At that time, some agencies predicted that a national outbreak of avian influenza would probably kill 750000 British people Similar decisions have been made in other countries, with Tamiflu widely designated for use in the 2009 swine flu outbreak But there is no credible way that Tamiflu can prevent a pandemic, the report said The report also revealed that the drug has many side effects, including nausea, headache, mental activity, kidney disease and hyperglycemia "I don't think the entire £ 500 million cost has produced any way to benefit human health, but it may harm human health," said Carl heneghan, a professor of evidence-based medicine at Oxford University, one of the authors of the report "The evidence of drug effectiveness is flawed and misleads the public in drug abuse." Researchers from the international collaborative group on evidence-based medicine point out that Tamiflu is not effective and does not target any individual or organization, but that every link from manufacturers to regulations and government regulation has responsibilities But Roche disagreed, warning that "the report could have a serious impact on public health." Dr Daniel thurley, director of its UK medical center, said: "the decisive part of the study is randomized controlled trials, which have been shared with regulators, and then Tamiflu has been approved in more than 100 countries to prevent influenza "He said," the international collaborative group on evidence-based medicine used wrong data and unorthodox side-effect analysis methods, which alone could not reflect the efficacy of Tamiflu in preventing influenza They should replenish their stockpiles, otherwise when the flu is raging, we have no way We don't have any vaccines in the first six months of the outbreak "Roche did not release their research data The report will enable Roche to disclose previously hidden data on the efficacy and side effects of Tamiflu It concluded that for adults, Tamiflu reduced flu symptoms from 7 days to 6.3 days, compared with 5.8 days in children "We review all published data on a regular basis and will take the report of the international collaborative group on evidence-based medicine seriously," the Department said "