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    Home > Active Ingredient News > Drugs Articles > Test method for internal stress of sodium calcium glass infusion bottle

    Test method for internal stress of sodium calcium glass infusion bottle

    • Last Update: 2017-09-13
    • Source: Internet
    • Author: User
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    Abstract: the glass infusion bottle, also known as large volume injection glass bottle, usually refers to the liquid sterilization preparation whose capacity is more than or equal to 50ml and directly input into the body by intravenous drip According to its clinical use, the large infusion bottle can be roughly divided into Category 5: fluid balance infusion, nutrition infusion, blood volume expansion infusion, therapeutic drug infusion and dialysis contrast Since the clinical application, the packaging containers of infusion products have experienced three generations of changes At present, there are four kinds of packaging materials in the infusion Market in China: glass bottles, plastic bottles, non PVC soft bags and vertical soft bags Non PVC soft bag infusion packaging technology is safe and effective, which meets the requirements of medicine and environmental protection It is the main development direction of infusion packaging technology Key words: large infusion bottle, glass bottle, injection bottle, polarized light stress, glass stress value, optical path difference test standard: ybb00032005-2015 sodium calcium glass infusion bottle, ybb00162003-2015 internal stress measurement method, text: The main characteristics of glass packaging containers are: non-toxic, tasteless; transparent, beautiful, good barrier, airtight, rich and common raw materials, low price, and can be used repeatedly It has the advantages of heat resistance, pressure resistance and cleaning resistance It can be sterilized at high temperature and stored at low temperature Because of its many advantages, it is widely used in medicine and food industry Because it is fragile and difficult to transport in the process of transportation and use, there are other types of packaging in the industry, such as polypropylene, polyethylene infusion bottles, multi-layer co extrusion infusion bags and other packaging The internal stress test of glass containers is a routine test item for glass bottles It is not only suitable for infusion bottles, but also for similar packaging vials such as Xilin bottles and ampoules Test items: [internal stress] test instrument: 1 Polarizing stress instrument 2 Wall thickness gauge test method A low internal stress test of infusion bottle (1) put a quarter wave plate into the field of view, adjust the zero point of polarizing stress instrument to make it appear dark field of view (2) Place the test object in the field of view, and observe the bottom from the mouth At this time, a dark cross will appear in the field of view (Figure 1) (3) Turn the polarizer so that the dark cross is separated into two arcs moving in the opposite direction (Fig 2) (4) Observe that there will be blue gray on the concave side and brown on the convex side of the arc (5) Rotate the test object around the axis, find out the Zui high stress point, rotate the polarizer until the blue gray is replaced by the brown, record the rotation angle of the polarizer at this time, and measure the thickness of the point Fig 1 Fig 2 b internal stress test of infusion bottle wall (1) put a quarter wave plate into the field of view, adjust the zero point of polarizing stress instrument to make it appear dark field of view (2) Put the test object into the field of view, make the axis of the test object and the plane of polarization 45 ° (3) observe the big stress area of Zui with different light and shade on the side wall (4) Record the placement angle of the inspection mirror in the large stress area of Zui, and measure the thickness of both sides of the wall (sum of them) Test results: standard requirements: [internal stress] take appropriate amount of this product, and the optical path difference caused by the large * stress of Zui annealed according to the internal stress measurement method (ybb00162003-2015) shall not exceed 40 nm / min If the stress of the test object is small, the dark cross will be blurred Results calculation: in the formula of δ = t / T = θ x3.14/t, δ is the internal stress of the test article, nm / mm; t is the optical path difference of the tested part, nm; t is the total thickness of the light passing part of the tested part, mm; θ is the rotation angle of the polarizer (when the Zui stress is measured); 3.14 is the constant of white light source (effective wavelength is about 565nm) If you need to know more about medical packaging products, please call Jinan Saicheng Electronic Technology Co., Ltd.
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